Methyl Cholate

Name: Methyl Cholate
Brand: Vaqora Chemicals
SKU: VQ-034507

About Methyl Cholate

Listed under CAS 1448-36-8, Methyl Cholate is an impurity of Chenodeoxycholic acid available from Vaqora Chemicals. With the molecular formula C25H42O5, it has a molar mass of 422.6 g/mol. Alternative names: Cholic Acid Methyl Ester and Chenodeoxycholic acid 12-hydroxy methyl ester.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Chenodeoxycholic acid, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl Cholate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Chenodeoxycholic acid

View every impurity, metabolite and intermediate we list for Chenodeoxycholic acid.

Chenodeoxycholic acid impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl Cholate
Catalogue No.	VQ-034507
CAS Number	1448-36-8
IUPAC name	methyl (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
Molecular formula	C₂₅H₄₂O₅
Molecular weight	422.6 g/mol
Exact mass	422.3032
Grade	Reference Standard
HSN code	38229090
InChIKey	DLYVTEULDNMQAR-SRNOMOOLSA-N
SMILES	C[C@H](CCC(=O)OC)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
PubChem CID	10960835

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	3 / 5
TPSA	87 Å²
Synonyms	Cholic Acid Methyl Ester, Chenodeoxycholic acid 12-hydroxy methyl ester, Cholic acid, methyl ester, Cholan-24-oic acid, 3,7,12-trihydroxy-, methyl ester, (3alpha,5beta,7alpha,12alpha)-, Methyl 3.alpha.,7.alpha.,12.alpha.-trihydroxy-5.beta.-cholanoate, Cholan-24-oic acid, 3,7,12-trihydroxy-, methyl ester, (3, A,5, A,7, A,12, A)-, Methyl 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-ate, 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oic acid Methyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl Cholate?

The CAS Registry Number of Methyl Cholate is 1448-36-8. It is also known as Cholic Acid Methyl Ester, Chenodeoxycholic acid 12-hydroxy methyl ester, Cholic acid, methyl ester.

What is the molecular formula and molecular weight of Methyl Cholate?

Methyl Cholate has the molecular formula C25H42O5 and a molecular weight of 422.6 g/mol.

What is Methyl Cholate used for?

Methyl Cholate is supplied as a characterised reference material related to Chenodeoxycholic acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl Cholate can I order?

We supply Methyl Cholate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl Cholate?

Yes. Every lot of Methyl Cholate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl Cholate be shipped internationally?

Yes. Methyl Cholate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.