Metolazone

Name: Metolazone
Brand: Vaqora Chemicals
SKU: VQ-026654

About Metolazone

Metolazone is a high-purity reference standard of Metolazone carrying the CAS registry number 17560-51-9. Formula C16H16ClN3O3S, molecular weight 365.8 g/mol. The IUPAC name is 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide. It is also known as Metalozone or metozalone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Metolazone standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Metolazone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Metolazone

View every impurity, metabolite and intermediate we list for Metolazone.

Metolazone impurities

Specifications & identifiers

Chemical identifiers
Product name	Metolazone
Catalogue No.	VQ-026654
CAS Number	17560-51-9
IUPAC name	7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
Molecular formula	C₁₆H₁₆ClN₃O₃S
Molecular weight	365.8 g/mol
Exact mass	365.0601
Grade	Reference Standard
HSN code	38229090
InChIKey	AQCHWTWZEMGIFD-UHFFFAOYSA-N
SMILES	CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl
PubChem CID	4170

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	2 / 5
TPSA	101 Å²
Synonyms	Metalozone, metozalone, 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, Metazoline, 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-, 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide, 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone, 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide, 6-Quinazolinesulfonamide, 1,2,3,4-tetrahydro-7-chloro-2-methyl-4-oxo-3-o-tolyl-, 7-Chloro-2-methyl-4-oxo-3-(o-tolyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide, Metolazone (Zaroxolyn)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Metolazone?

The CAS Registry Number of Metolazone is 17560-51-9. It is also known as Metalozone, metozalone, 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide.

What is the molecular formula and molecular weight of Metolazone?

Metolazone has the molecular formula C16H16ClN3O3S and a molecular weight of 365.8 g/mol. Its IUPAC name is 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide.

What is Metolazone used for?

Metolazone is supplied as a characterised reference material related to Metolazone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metolazone can I order?

We supply Metolazone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metolazone?

Yes. Every lot of Metolazone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metolazone be shipped internationally?

Yes. Metolazone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.