Mitapivat

Name: Mitapivat
Brand: Vaqora Chemicals
SKU: VQ-031957

About Mitapivat

Listed under CAS 1260075-17-9, Mitapivat is a high-purity reference standard of Mitapivat available from Vaqora Chemicals. With the molecular formula C24H26N4O3S, it has a molar mass of 450.6 g/mol. Its systematic (IUPAC) name is N-[4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide. Alternative names: PKR-IN-1 and AG-348.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Mitapivat standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Mitapivat is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Mitapivat

View every impurity, metabolite and intermediate we list for Mitapivat.

Mitapivat impurities

Specifications & identifiers

Chemical identifiers
Product name	Mitapivat
Catalogue No.	VQ-031957
CAS Number	1260075-17-9
IUPAC name	N-[4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide
Molecular formula	C₂₄H₂₆N₄O₃S
Molecular weight	450.6 g/mol
Exact mass	450.1726
Grade	Reference Standard
HSN code	38229090
InChIKey	XAYGBKHKBBXDAK-UHFFFAOYSA-N
SMILES	C1CC1CN2CCN(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C4=CC=CC5=C4N=CC=C5
PubChem CID	59634741

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 6
TPSA	91 Å²
Synonyms	PKR-IN-1, AG-348, 8-Quinolinesulfonamide, N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-, N-(4-((4-(Cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-8-quinolinesulfonamide, PK-R Activator AG-348, AG 348, Red Cell Pyruvate Kinase Activator AG-348, n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide, PKM2 activator 1020, N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide, Mitapivat (AG-348), EX-A2626

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Mitapivat?

The CAS Registry Number of Mitapivat is 1260075-17-9. It is also known as PKR-IN-1, AG-348, 8-Quinolinesulfonamide, N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-.

What is the molecular formula and molecular weight of Mitapivat?

Mitapivat has the molecular formula C24H26N4O3S and a molecular weight of 450.6 g/mol. Its IUPAC name is N-[4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide.

What is Mitapivat used for?

Mitapivat is supplied as a characterised reference material related to Mitapivat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Mitapivat can I order?

We supply Mitapivat in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Mitapivat?

Yes. Every lot of Mitapivat is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Mitapivat be shipped internationally?

Yes. Mitapivat is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.