Mitoxantrone

Name: Mitoxantrone
Brand: Vaqora Chemicals
SKU: VQ-044572

About Mitoxantrone

Mitoxantrone is a high-purity reference standard of Mitoxantrone carrying the CAS registry number 65271-80-9. Its molecular formula is C22H28N4O6 and its molecular weight is 444.5 g/mol. Systematically, it is named 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione. It is also known as Mitozantrone or Mitoxanthrone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Mitoxantrone, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Mitoxantrone

View every impurity, metabolite and intermediate we list for Mitoxantrone.

Mitoxantrone impurities

Specifications & identifiers

Chemical identifiers
Product name	Mitoxantrone
Catalogue No.	VQ-044572
CAS Number	65271-80-9
IUPAC name	1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione
Molecular formula	C₂₂H₂₈N₄O₆
Molecular weight	444.5 g/mol
Exact mass	444.2009
Grade	Reference Standard
HSN code	38229090
InChIKey	KKZJGLLVHKMTCM-UHFFFAOYSA-N
SMILES	C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO
PubChem CID	4212

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	8 / 10
TPSA	163 Å²
Synonyms	Mitozantrone, Mitoxanthrone, Misostol, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione, 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, Acetate, Mitoxantrone, 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, dihydroxyanthracenedione, mitoyantrone hydrochloride, 1,3-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-9, 10-anthracenedione, 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-9, 10-anthroquinone

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H351Suspected of causing cancer
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P273, P280, P318, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Mitoxantrone?

The CAS Registry Number of Mitoxantrone is 65271-80-9. It is also known as Mitozantrone, Mitoxanthrone, Misostol.

What is the molecular formula and molecular weight of Mitoxantrone?

Mitoxantrone has the molecular formula C22H28N4O6 and a molecular weight of 444.5 g/mol. Its IUPAC name is 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione.

What is Mitoxantrone used for?

Mitoxantrone is supplied as a characterised reference material related to Mitoxantrone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Mitoxantrone can I order?

We supply Mitoxantrone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Mitoxantrone?

Yes. Every lot of Mitoxantrone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Mitoxantrone be shipped internationally?

Yes. Mitoxantrone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.