N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H… 73829-38-6

Name: N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide
Brand: Vaqora Chemicals
SKU: VQ-023083

About N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide

Listed under CAS 73829-38-6, N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide is a nitrosamine impurity of Metamizole available from Vaqora Chemicals. The compound has the formula C12H14N4O2, corresponding to a molecular weight of 246.27 g/mol. Systematically, it is named N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-N-methylnitrous amide. Alternative names: 4-(N-Methyl-N-nitroso)aminoantipyrine and N-nitrosomethylaminoantipyrine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Metamizole

View every impurity, metabolite and intermediate we list for Metamizole.

Metamizole impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide
Catalogue No.	VQ-023083
CAS Number	73829-38-6
IUPAC name	N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-N-methylnitrous amide
Molecular formula	C₁₂H₁₄N₄O₂
Molecular weight	246.27 g/mol
Exact mass	246.1117
Grade	Reference Standard
HSN code	38229090
InChIKey	PJVMURIFUSQEOU-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)N=O
PubChem CID	126438

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	0 / 5
TPSA	56.2 Å²
Synonyms	4-(N-Methyl-N-nitroso)aminoantipyrine, N-nitrosomethylaminoantipyrine, N-nitroso-methylaminoantipyrine, N-NMAA, 1,2-Dihydro-1,5-dimethyl-4-(methylnitrosoamino)-2-phenyl-3H-pyrazol-3-one, 4-Nitroso-N-methylaminoantipyrine, Antipyrine, 4-(methylnitrosamino)-, 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(methylnitrosoamino)-2-phenyl-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide?

The CAS Registry Number of N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide is 73829-38-6. It is also known as 4-(N-Methyl-N-nitroso)aminoantipyrine, N-nitrosomethylaminoantipyrine, N-nitroso-methylaminoantipyrine.

What is the molecular formula and molecular weight of N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide?

N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide has the molecular formula C12H14N4O2 and a molecular weight of 246.27 g/mol. Its IUPAC name is N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-N-methylnitrous amide.

What is N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide used for?

N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide is supplied as a characterised reference material related to Metamizole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide can I order?

We supply N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide?

Yes. Every lot of N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide be shipped internationally?

Yes. N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.