N-(2-Hydroxyethyl)phthalimide

Name: N-(2-Hydroxyethyl)phthalimide
Brand: Vaqora Chemicals
SKU: VQ-013590

About N-(2-Hydroxyethyl)phthalimide

N-(2-Hydroxyethyl)phthalimide is a process intermediate or related compound of Amlodipine carrying the CAS registry number 3891-07-4. Formula C10H9NO3, molecular weight 191.18 g/mol. The IUPAC name is 2-(2-hydroxyethyl)isoindole-1,3-dione. Alternative names: 2-(2-Hydroxyethyl)-1H-isoindole-1,3(2H)-dione and 2-(2-Hydroxyethyl)isoindoline-1,3-dione.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Amlodipine, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N-(2-Hydroxyethyl)phthalimide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Amlodipine

View every impurity, metabolite and intermediate we list for Amlodipine.

Amlodipine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(2-Hydroxyethyl)phthalimide
Catalogue No.	VQ-013590
CAS Number	3891-07-4
IUPAC name	2-(2-hydroxyethyl)isoindole-1,3-dione
Molecular formula	C₁₀H₉NO₃
Molecular weight	191.18 g/mol
Exact mass	191.0582
Grade	Reference Standard
HSN code	2933
InChIKey	MWFLUYFYHANMCM-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)N(C2=O)CCO
PubChem CID	77499

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 3
TPSA	57.6 Å²
Synonyms	2-(2-Hydroxyethyl)-1H-isoindole-1,3(2H)-dione, 2-(2-Hydroxyethyl)isoindoline-1,3-dione, 2-(N-Phthalimidyl)ethyl alcohol, 2-Phthalimidoethanol, N-Hydroxyethylphthalimide, 1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxyethyl)-, 2-Hydroxyethylphthalimide, N-[2-hydroxyethyl]phthalimide, 2-hydroxyethylphtalimide, Phthalimide, N-(2-hydroxyethyl)-, Phthalimide, N-2-hydroxyethyl-, 2-(2-hydroxy-ethyl)-isoindole-1,3-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 3891-07-4

Synthesis

n-(2-Hydroxyethyl)phthalimide, 97%

CAS: 3891-07-4
Formula: C₁₀H₉NO₃
MW: 191.18 g/mol

VQ-012610

Frequently asked questions

What is the CAS number of N-(2-Hydroxyethyl)phthalimide?

The CAS Registry Number of N-(2-Hydroxyethyl)phthalimide is 3891-07-4. It is also known as 2-(2-Hydroxyethyl)-1H-isoindole-1,3(2H)-dione, 2-(2-Hydroxyethyl)isoindoline-1,3-dione, 2-(N-Phthalimidyl)ethyl alcohol.

What is the molecular formula and molecular weight of N-(2-Hydroxyethyl)phthalimide?

N-(2-Hydroxyethyl)phthalimide has the molecular formula C10H9NO3 and a molecular weight of 191.18 g/mol. Its IUPAC name is 2-(2-hydroxyethyl)isoindole-1,3-dione.

What is N-(2-Hydroxyethyl)phthalimide used for?

N-(2-Hydroxyethyl)phthalimide is supplied as a characterised reference material related to Amlodipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(2-Hydroxyethyl)phthalimide can I order?

We supply N-(2-Hydroxyethyl)phthalimide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(2-Hydroxyethyl)phthalimide?

Yes. Every lot of N-(2-Hydroxyethyl)phthalimide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(2-Hydroxyethyl)phthalimide be shipped internationally?

Yes. N-(2-Hydroxyethyl)phthalimide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.