N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide

Name: N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide
Brand: Vaqora Chemicals
SKU: VQ-032531

About N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide

Vaqora Chemicals supplies N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide, a nitrosamine impurity of Sunitinib registered under CAS number 351-09-7. The compound has the formula C8H7FN2O2, corresponding to a molecular weight of 182.15 g/mol. Systematically, it is named (2E)-N-(4-fluorophenyl)-2-hydroxyiminoacetamide. Alternative names: 4-Fluoroisonitrosoacetanilide and 4'-fluoroisonitrosoacetanilide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Sunitinib

View every impurity, metabolite and intermediate we list for Sunitinib.

Sunitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide
Catalogue No.	VQ-032531
CAS Number	351-09-7
IUPAC name	(2E)-N-(4-fluorophenyl)-2-hydroxyiminoacetamide
Molecular formula	C₈H₇FN₂O₂
Molecular weight	182.15 g/mol
Exact mass	182.0492
Grade	Reference Standard
HSN code	38229090
InChIKey	DXSBFTGUEOWLSD-BJMVGYQFSA-N
SMILES	C1=CC(=CC=C1NC(=O)/C=N/O)F
PubChem CID	6869015

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 4
TPSA	61.7 Å²
Synonyms	4-Fluoroisonitrosoacetanilide, (2E)-N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide, N-(4-fluorophenyl)-2-(N-hydroxyimino)acetamide, (E)-N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide, (2E)-N-(4-fluorophenyl)-2-(N-hydroxyimino)acetamide, 4'-fluoroisonitrosoacetanilide, (2E)-N-(4-fluorophenyl)-2-(hydroxyimino)ethanamide, (2E)-N-(4-fluorophenyl)-2-hydroxyimino-acetamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide?

The CAS Registry Number of N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide is 351-09-7. It is also known as 4-Fluoroisonitrosoacetanilide, (2E)-N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide, N-(4-fluorophenyl)-2-(N-hydroxyimino)acetamide.

What is the molecular formula and molecular weight of N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide?

N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide has the molecular formula C8H7FN2O2 and a molecular weight of 182.15 g/mol. Its IUPAC name is (2E)-N-(4-fluorophenyl)-2-hydroxyiminoacetamide.

What is N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide used for?

N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide is supplied as a characterised reference material related to Sunitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide can I order?

We supply N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide?

Yes. Every lot of N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide be shipped internationally?

Yes. N-(4-Fluorophenyl)-2-(hydroxyimino)acetamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.