N-Acetyl-L-leucine

Name: N-Acetyl-L-leucine
Brand: Vaqora Chemicals
SKU: VQ-032378

About N-Acetyl-L-leucine

Vaqora Chemicals supplies N-Acetyl-L-leucine, a process intermediate or related compound of Leucine registered under CAS number 1188-21-2. With the molecular formula C8H15NO3, it has a molar mass of 173.21 g/mol. Its systematic (IUPAC) name is (2S)-2-acetamido-4-methylpentanoic acid. Common synonyms include Acetyl-L-leucine and N-Acetylleucine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Leucine, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Acetyl-L-leucine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Leucine

View every impurity, metabolite and intermediate we list for Leucine.

Leucine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Acetyl-L-leucine
Catalogue No.	VQ-032378
CAS Number	1188-21-2
IUPAC name	(2S)-2-acetamido-4-methylpentanoic acid
Molecular formula	C₈H₁₅NO₃
Molecular weight	173.21 g/mol
Exact mass	173.1052
InChIKey	WXNXCEHXYPACJF-ZETCQYMHSA-N
SMILES	CC(C)C[C@@H](C(=O)O)NC(=O)C
PubChem CID	70912

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	2 / 3
TPSA	66.4 Å²
Synonyms	Acetyl-L-leucine, N-Acetylleucine, L-Acetylleucine, (S)-2-Acetamido-4-methylpentanoic acid, N-acetyl-leucine, Levacetylleucine, Leucine, N-acetyl-, L-, n-acetyl leucine, Ac-Leu-OH, n-acetyl-L-leucin, L-Leucine, N-acetyl-, (2S)-2-acetamido-4-methyl-pentanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Acetyl-L-leucine?

The CAS Registry Number of N-Acetyl-L-leucine is 1188-21-2. It is also known as Acetyl-L-leucine, N-Acetylleucine, L-Acetylleucine.

What is the molecular formula and molecular weight of N-Acetyl-L-leucine?

N-Acetyl-L-leucine has the molecular formula C8H15NO3 and a molecular weight of 173.21 g/mol. Its IUPAC name is (2S)-2-acetamido-4-methylpentanoic acid.

What is N-Acetyl-L-leucine used for?

N-Acetyl-L-leucine is supplied as a characterised reference material related to Leucine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Acetyl-L-leucine can I order?

We supply N-Acetyl-L-leucine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Acetyl-L-leucine?

Yes. Every lot of N-Acetyl-L-leucine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Acetyl-L-leucine be shipped internationally?

Yes. N-Acetyl-L-leucine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.