N-Boc-trans-4-hydroxy-D-proline

Name: N-Boc-trans-4-hydroxy-D-proline
Brand: Vaqora Chemicals
SKU: VQ-049469

About N-Boc-trans-4-hydroxy-D-proline

Listed under CAS 147266-92-0, N-Boc-trans-4-hydroxy-D-proline is a metabolite / degradant standard available from Vaqora Chemicals. Formula C10H17NO5, molecular weight 231.25 g/mol. The IUPAC name is (2R,4S)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid. It is also known as N-Boc-4-hydroxy-D-proline, trans- or N-Boc-4-hydroxy-D-proline, (4S)-(+)-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N-Boc-trans-4-hydroxy-D-proline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Specifications & identifiers

Chemical identifiers
Product name	N-Boc-trans-4-hydroxy-D-proline
Catalogue No.	VQ-049469
CAS Number	147266-92-0
IUPAC name	(2R,4S)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
Molecular formula	C₁₀H₁₇NO₅
Molecular weight	231.25 g/mol
Exact mass	231.1107
Grade	Reference Standard
HSN code	38229090
InChIKey	BENKAPCDIOILGV-NKWVEPMBSA-N
SMILES	CC(C)(C)OC(=O)N1C[C@H](C[C@@H]1C(=O)O)O
PubChem CID	688615

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	2 / 5
TPSA	87.1 Å²
Synonyms	N-Boc-4-hydroxy-D-proline, trans-, (4S)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline, N-Boc-4-hydroxy-D-proline, (4S)-(+)-, (2r,4s)-1-(tert-butoxycarbonyl)-4-hydroxy-2-pyrrolidinecarboxylic acid, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2R-trans)-, rac-(2R,4S)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid, rac-(2R,4S)-1-((tert-butoxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid, (2R,4S)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid, (2R,4S)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid, trans-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid, N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline, Boc-trans-D-Hyp-OH

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Boc-trans-4-hydroxy-D-proline?

The CAS Registry Number of N-Boc-trans-4-hydroxy-D-proline is 147266-92-0. It is also known as N-Boc-4-hydroxy-D-proline, trans-, (4S)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline, N-Boc-4-hydroxy-D-proline, (4S)-(+)-.

What is the molecular formula and molecular weight of N-Boc-trans-4-hydroxy-D-proline?

N-Boc-trans-4-hydroxy-D-proline has the molecular formula C10H17NO5 and a molecular weight of 231.25 g/mol. Its IUPAC name is (2R,4S)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid.

Which grade and pack sizes of N-Boc-trans-4-hydroxy-D-proline can I order?

We supply N-Boc-trans-4-hydroxy-D-proline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Boc-trans-4-hydroxy-D-proline?

Yes. Every lot of N-Boc-trans-4-hydroxy-D-proline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Boc-trans-4-hydroxy-D-proline be shipped internationally?

Yes. N-Boc-trans-4-hydroxy-D-proline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.