N-Demethyl Erythromycin A

Name: N-Demethyl Erythromycin A
Brand: Vaqora Chemicals
SKU: VQ-021184

About N-Demethyl Erythromycin A

N-Demethyl Erythromycin A (CAS 992-62-1) is a metabolite or degradation product of Erythromycin offered by Vaqora Chemicals. With the molecular formula C36H65NO13, it has a molar mass of 719.9 g/mol. Common synonyms include 3'-Demethylerythromyon and Des-N-methylerythromycin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Erythromycin, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer N-Demethyl Erythromycin A in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Erythromycin

View every impurity, metabolite and intermediate we list for Erythromycin.

Erythromycin impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Demethyl Erythromycin A
Catalogue No.	VQ-021184
CAS Number	992-62-1
IUPAC name	(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-6-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
Molecular formula	C₃₆H₆₅NO₁₃
Molecular weight	719.9 g/mol
Exact mass	719.4456
Grade	Reference Standard
HSN code	38229090
InChIKey	TXOOBKBDBNRQCF-QNPWSHAKSA-N
SMILES	CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)NC)O)(C)O)C)C)O)(C)O
PubChem CID	10010092

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	6 / 14
TPSA	203 Å²
Synonyms	3'-Demethylerythromyon, Des-N-methylerythromycin, Erythromyon, 3'-demethyl-, N-Desmethyl Erythromycin, N-desmethylerythro-mycin a, N-Desmethyl Erythromycin A

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Demethyl Erythromycin A?

The CAS Registry Number of N-Demethyl Erythromycin A is 992-62-1. It is also known as 3'-Demethylerythromyon, Des-N-methylerythromycin, Erythromyon, 3'-demethyl-.

What is the molecular formula and molecular weight of N-Demethyl Erythromycin A?

N-Demethyl Erythromycin A has the molecular formula C36H65NO13 and a molecular weight of 719.9 g/mol.

What is N-Demethyl Erythromycin A used for?

N-Demethyl Erythromycin A is supplied as a characterised reference material related to Erythromycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Demethyl Erythromycin A can I order?

We supply N-Demethyl Erythromycin A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Demethyl Erythromycin A?

Yes. Every lot of N-Demethyl Erythromycin A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Demethyl Erythromycin A be shipped internationally?

Yes. N-Demethyl Erythromycin A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.