N-Desmethyl Asenapine

Name: N-Desmethyl Asenapine
Brand: Vaqora Chemicals
SKU: VQ-035133

About N-Desmethyl Asenapine

N-Desmethyl Asenapine (CAS 128915-56-0) is a metabolite or degradation product of Asenapine offered by Vaqora Chemicals. The compound has the formula C16H14ClNO, corresponding to a molecular weight of 271.74 g/mol. The IUPAC name is (2S,6S)-9-chloro-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene. It is also known as Asenapine metabolite PC19 or N-Desmethyl Asenapine HCl.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Asenapine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Desmethyl Asenapine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Asenapine

View every impurity, metabolite and intermediate we list for Asenapine.

Asenapine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Asenapine
Catalogue No.	VQ-035133
CAS Number	128915-56-0
IUPAC name	(2S,6S)-9-chloro-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene
Molecular formula	C₁₆H₁₄ClNO
Molecular weight	271.74 g/mol
Exact mass	271.0764
Grade	Reference Standard
HSN code	38229090
InChIKey	DQUCRGAOGUQHJQ-ZIAGYGMSSA-N
SMILES	C1[C@H]2[C@H](CN1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24
PubChem CID	44568616

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	1 / 2
TPSA	21.3 Å²
Synonyms	Asenapine metabolite PC19, trans-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole, 1H-Dibenz(2,3:6,7)oxepino(4,5-C)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-, (3aR,12bR)-rel-, 1H-Dibenz(2,3:6,7)oxepino(4,5-C)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-, trans-, Rel-(3aR,12bR)-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenz(2,3:6,7)oxepino(4,5-C)pyrrole, N-Desmethyl Asenapine HCl, (3aS,12bS)-5-Chloro-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Asenapine?

The CAS Registry Number of N-Desmethyl Asenapine is 128915-56-0. It is also known as Asenapine metabolite PC19, trans-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole, 1H-Dibenz(2,3:6,7)oxepino(4,5-C)pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-, (3aR,12bR)-rel-.

What is the molecular formula and molecular weight of N-Desmethyl Asenapine?

N-Desmethyl Asenapine has the molecular formula C16H14ClNO and a molecular weight of 271.74 g/mol. Its IUPAC name is (2S,6S)-9-chloro-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene.

What is N-Desmethyl Asenapine used for?

N-Desmethyl Asenapine is supplied as a characterised reference material related to Asenapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Asenapine can I order?

We supply N-Desmethyl Asenapine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Asenapine?

Yes. Every lot of N-Desmethyl Asenapine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Asenapine be shipped internationally?

Yes. We export N-Desmethyl Asenapine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.