N-Desmethyl Desacetyl Diltiazem

Name: N-Desmethyl Desacetyl Diltiazem
Brand: Vaqora Chemicals
SKU: VQ-007200

About N-Desmethyl Desacetyl Diltiazem

N-Desmethyl Desacetyl Diltiazem (CAS 86408-44-8) is a metabolite or degradation product of Diltiazem offered by Vaqora Chemicals with a typical assay of 98.16%. With the molecular formula C19H22N2O3S, it has a molar mass of 358.5 g/mol. Its systematic (IUPAC) name is (2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one. Alternative names: Deacetyl-N-demethyl-d-diltiazem and Deacetyl-N-demethyldiltiazem.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Diltiazem, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Desacetyl Diltiazem
Catalogue No.	VQ-007200
CAS Number	86408-44-8
IUPAC name	(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one
Molecular formula	C₁₉H₂₂N₂O₃S
Molecular weight	358.5 g/mol
Exact mass	358.1351
Grade	Reference Standard
Purity / assay	98.16%
HSN code	38229090
InChIKey	HNXJRKQNTGIDDU-MSOLQXFVSA-N
SMILES	CNCCN1C2=CC=CC=C2S[C@H]([C@H](C1=O)O)C3=CC=C(C=C3)OC
PubChem CID	158945

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 5
TPSA	87.1 Å²
Synonyms	Deacetyl-N-demethyl-d-diltiazem, Deacetyl-N-demethyldiltiazem, Deacetyl-N-monodemethyldiltiazem, Deacetyl-N-monodesmethyldiltiazem, N-Demethyldeacetyldiltiazem, N-Desmethyldeacetyldiltiazem, Desacetyl-N-monodesmethyldiltiazem

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Desacetyl Diltiazem?

The CAS Registry Number of N-Desmethyl Desacetyl Diltiazem is 86408-44-8. It is also known as Deacetyl-N-demethyl-d-diltiazem, Deacetyl-N-demethyldiltiazem, Deacetyl-N-monodemethyldiltiazem.

What is the molecular formula and molecular weight of N-Desmethyl Desacetyl Diltiazem?

N-Desmethyl Desacetyl Diltiazem has the molecular formula C19H22N2O3S and a molecular weight of 358.5 g/mol. Its IUPAC name is (2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one.

What is N-Desmethyl Desacetyl Diltiazem used for?

N-Desmethyl Desacetyl Diltiazem is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Desacetyl Diltiazem can I order?

We supply N-Desmethyl Desacetyl Diltiazem in Reference Standard (98.16%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Desacetyl Diltiazem?

Yes. Every lot of N-Desmethyl Desacetyl Diltiazem is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Desacetyl Diltiazem be shipped internationally?

Yes. We export N-Desmethyl Desacetyl Diltiazem worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.