N-Desmethyl Galanthamine

Name: N-Desmethyl Galanthamine
Brand: Vaqora Chemicals
SKU: VQ-022743

About N-Desmethyl Galanthamine

N-Desmethyl Galanthamine (CAS 41303-74-6) is a metabolite or degradation product of Galantamine offered by Vaqora Chemicals. With the molecular formula C16H19NO3, it has a molar mass of 273.33 g/mol. Systematically, it is named (1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol. Common synonyms include Norgalanthamine and N-Desmethylgalantamine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Galantamine, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Galanthamine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Galantamine

View every impurity, metabolite and intermediate we list for Galantamine.

Galantamine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Galanthamine
Catalogue No.	VQ-022743
CAS Number	41303-74-6
IUPAC name	(1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
Molecular formula	C₁₆H₁₉NO₃
Molecular weight	273.33 g/mol
Exact mass	273.1365
Grade	Reference Standard
HSN code	38229090
InChIKey	AIXQQSTVOSFSMO-RBOXIYTFSA-N
SMILES	COC1=C2C3=C(CNCC[C@]34C=C[C@@H](C[C@@H]4O2)O)C=C1
PubChem CID	9838394

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	2 / 4
TPSA	50.7 Å²
Synonyms	Norgalanthamine, N-Desmethylgalantamine, N-Norgalanthamine, Norgalantamine, N-Desmethyl galantamine, N-Demethylgalanthamine, Stephaoxocanidine derivative, (4aS,6R,8aS)-3-Methoxy-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol, (4aS,6R,8aS)-3-methoxy-5,6,9,10,11,12-hexahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol, (-)-N-Demethylgalanthamine, Galanthamine, 10-demethyl-

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H331Toxic if inhaled

Precautionary statements: P261, P264, P270, P271, P272, P280, P301 + P316, P302 + P352, P304 + P340, P316, P321, P330, P332 + P317, P333 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Galanthamine?

The CAS Registry Number of N-Desmethyl Galanthamine is 41303-74-6. It is also known as Norgalanthamine, N-Desmethylgalantamine, N-Norgalanthamine.

What is the molecular formula and molecular weight of N-Desmethyl Galanthamine?

N-Desmethyl Galanthamine has the molecular formula C16H19NO3 and a molecular weight of 273.33 g/mol. Its IUPAC name is (1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol.

What is N-Desmethyl Galanthamine used for?

N-Desmethyl Galanthamine is supplied as a characterised reference material related to Galantamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Galanthamine can I order?

We supply N-Desmethyl Galanthamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Galanthamine?

Yes. Every lot of N-Desmethyl Galanthamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Galanthamine be shipped internationally?

Yes. N-Desmethyl Galanthamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.