N-Desmethyl sertraline

Name: N-Desmethyl sertraline
Brand: Vaqora Chemicals
SKU: VQ-033821

About N-Desmethyl sertraline

Vaqora Chemicals supplies N-Desmethyl sertraline, a metabolite or degradation product of Sertraline registered under CAS number 87857-41-8. The compound has the formula C16H15Cl2N, corresponding to a molecular weight of 292.2 g/mol. Systematically, it is named (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine. It is also known as Norsertraline or Desmethylsertraline.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Sertraline, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Desmethyl sertraline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sertraline

View every impurity, metabolite and intermediate we list for Sertraline.

Sertraline impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl sertraline
Catalogue No.	VQ-033821
CAS Number	87857-41-8
IUPAC name	(1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Molecular formula	C₁₆H₁₅Cl₂N
Molecular weight	292.2 g/mol
Exact mass	291.0582
Grade	Reference Standard
HSN code	38229090
InChIKey	SRPXSILJHWNFMK-ZBEGNZNMSA-N
SMILES	C1C[C@@H](C2=CC=CC=C2[C@@H]1C3=CC(=C(C=C3)Cl)Cl)N
PubChem CID	114743

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	1 / 1
TPSA	26 Å²
Synonyms	Norsertraline, Desmethylsertraline, N-Demethylsertraline, Demethylsertraline, 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, (1S,4S)-, (1S,4S)-4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydronaphthalen-1-amine, cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine, (1s-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine, 4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-ylamine, HCl, rel-(1R,4R)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine, 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, (1S-cis)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl sertraline?

The CAS Registry Number of N-Desmethyl sertraline is 87857-41-8. It is also known as Norsertraline, Desmethylsertraline, N-Demethylsertraline.

What is the molecular formula and molecular weight of N-Desmethyl sertraline?

N-Desmethyl sertraline has the molecular formula C16H15Cl2N and a molecular weight of 292.2 g/mol. Its IUPAC name is (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine.

What is N-Desmethyl sertraline used for?

N-Desmethyl sertraline is supplied as a characterised reference material related to Sertraline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl sertraline can I order?

We supply N-Desmethyl sertraline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl sertraline?

Yes. Every lot of N-Desmethyl sertraline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl sertraline be shipped internationally?

Yes. We export N-Desmethyl sertraline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.