N-Desmethyl Sibutramine

Name: N-Desmethyl Sibutramine
Brand: Vaqora Chemicals
SKU: VQ-042157

About N-Desmethyl Sibutramine

N-Desmethyl Sibutramine is a metabolite or degradation product of Sibutramine carrying the CAS registry number 168835-59-4. With the molecular formula C16H24ClN, it has a molar mass of 265.82 g/mol. Systematically, it is named 1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine. It is also known as Desmethylsibutramine or mono-desmethylsibutramine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Sibutramine, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Desmethyl Sibutramine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sibutramine

View every impurity, metabolite and intermediate we list for Sibutramine.

Sibutramine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Sibutramine
Catalogue No.	VQ-042157
CAS Number	168835-59-4
IUPAC name	1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine
Molecular formula	C₁₆H₂₄ClN
Molecular weight	265.82 g/mol
Exact mass	265.1597
Grade	Reference Standard
HSN code	38229090
InChIKey	PLXKZKLXYHLWHR-UHFFFAOYSA-N
SMILES	CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)NC
PubChem CID	10199199

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	1 / 1
TPSA	12 Å²
Synonyms	Desmethylsibutramine, mono-desmethylsibutramine, N-Monodemethylsibutramine, Desmethyl Sibutramine, {1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}(methyl)amine, Desmethyl sibutramine hydrochloride salt, 1-(1-(4-chlorophenyl)cyclobutyl)-N,3-dimethylbutan-1-amine, 1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethyl-butan-1-amine, N-{1-[1-(4-Chlorophenyl)cyclobutyl]-3-methylbutyl}-N-methylamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Sibutramine?

The CAS Registry Number of N-Desmethyl Sibutramine is 168835-59-4. It is also known as Desmethylsibutramine, mono-desmethylsibutramine, N-Monodemethylsibutramine.

What is the molecular formula and molecular weight of N-Desmethyl Sibutramine?

N-Desmethyl Sibutramine has the molecular formula C16H24ClN and a molecular weight of 265.82 g/mol. Its IUPAC name is 1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine.

What is N-Desmethyl Sibutramine used for?

N-Desmethyl Sibutramine is supplied as a characterised reference material related to Sibutramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Sibutramine can I order?

We supply N-Desmethyl Sibutramine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Sibutramine?

Yes. Every lot of N-Desmethyl Sibutramine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Sibutramine be shipped internationally?

Yes. We export N-Desmethyl Sibutramine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.