N-Hydroxy Palbociclib

Name: N-Hydroxy Palbociclib
Brand: Vaqora Chemicals
SKU: VQ-027366

About N-Hydroxy Palbociclib

N-Hydroxy Palbociclib (CAS 2231085-26-8) is a metabolite or degradation product of Palbociclib offered by Vaqora Chemicals. Formula C24H29N7O3, molecular weight 463.5 g/mol. Its systematic (IUPAC) name is 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxypiperazin-1-yl)-2-pyridinyl]amino]-5-methylpyrido[2,3-d]pyrimidin-7-one. Common synonyms include Palbociclib N-Hydroxy Piperazine and Palbociclib 4-Piperazin-N-Oxide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Palbociclib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Hydroxy Palbociclib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Hydroxy Palbociclib
Catalogue No.	VQ-027366
CAS Number	2231085-26-8
IUPAC name	6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxypiperazin-1-yl)-2-pyridinyl]amino]-5-methylpyrido[2,3-d]pyrimidin-7-one
Molecular formula	C₂₄H₂₉N₇O₃
Molecular weight	463.5 g/mol
Exact mass	463.2332
Grade	Reference Standard
HSN code	38229090
InChIKey	GCUPXEXOHMNRRB-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)O)C5CCCC5)C(=O)C
PubChem CID	155664316

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 9
TPSA	115 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Hydroxy Palbociclib?

The CAS Registry Number of N-Hydroxy Palbociclib is 2231085-26-8. It is also known as Palbociclib N-Hydroxy Piperazine, Palbociclib 4-Piperazin-N-Oxide, Palbociclib metabolite M7.

What is the molecular formula and molecular weight of N-Hydroxy Palbociclib?

N-Hydroxy Palbociclib has the molecular formula C24H29N7O3 and a molecular weight of 463.5 g/mol. Its IUPAC name is 6-acetyl-8-cyclopentyl-2-[[5-(4-hydroxypiperazin-1-yl)-2-pyridinyl]amino]-5-methylpyrido[2,3-d]pyrimidin-7-one.

What is N-Hydroxy Palbociclib used for?

N-Hydroxy Palbociclib is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Hydroxy Palbociclib can I order?

We supply N-Hydroxy Palbociclib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Hydroxy Palbociclib?

Yes. Every lot of N-Hydroxy Palbociclib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Hydroxy Palbociclib be shipped internationally?

Yes. We export N-Hydroxy Palbociclib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.