N-Methyl-N-Nitroso p-Toluidine
Synonyms: P-Toluidine, N-methyl-N-nitroso- · 4-Methyl-N-nitroso-N-methylaniline · N,4-dimethyl-N-nitrosoaniline · N-Nitroso-N-methyl-p-toluidin
N-Methyl-N-Nitroso p-Toluidine (CAS 937-24-6) – nitrosamine impurity reference standard. C8H10N2O, MW 150.18. Vaqora Chemicals: COA, global shipping.
About N-Methyl-N-Nitroso p-Toluidine
N-Methyl-N-Nitroso p-Toluidine is a nitrosamine impurity of Toluidine carrying the CAS registry number 937-24-6. Its molecular formula is C8H10N2O and its molecular weight is 150.18 g/mol. Systematically, it is named N-methyl-N-(4-methylphenyl)nitrous amide. Alternative names: P-Toluidine, N-methyl-N-nitroso- and 4-Methyl-N-nitroso-N-methylaniline.
The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.
It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Toluidine, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies N-Methyl-N-Nitroso p-Toluidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.
Typical applications
- Nitrosamine risk assessment
- Trace LC-MS/MS quantitation
- Method validation (AMV)
- Regulatory submissions
Industries
View every impurity, metabolite and intermediate we list for Toluidine.
Toluidine impuritiesSpecifications & identifiers
| Product name | N-Methyl-N-Nitroso p-Toluidine |
|---|---|
| Catalogue No. | VQ-027225 |
| CAS Number | 937-24-6 |
| IUPAC name | N-methyl-N-(4-methylphenyl)nitrous amide |
| Molecular formula | C8H10N2O |
| Molecular weight | 150.18 g/mol |
| Exact mass | 150.0793 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | NEIPHSHFJXGGOS-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)N(C)N=O |
| PubChem CID | 101493 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.5 |
| H-bond donors / acceptors | 0 / 3 |
| TPSA | 32.7 Ų |
| Synonyms | P-Toluidine, N-methyl-N-nitroso-, 4-Methyl-N-nitroso-N-methylaniline, N,4-dimethyl-N-nitrosoaniline, N-Nitroso-N-methyl-p-toluidin, N-Methyl-N-(p-tolyl)nitrous amide, N-Nitroso N-Methyl-4-Methyl-Aniline, Benzenamine, N,4-dimethyl-N-nitroso-, 1-Methyl-1-(4-methylphenyl)-2-oxohydrazine # |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H301Toxic if swallowedH311Toxic in contact with skinH319Causes serious eye irritationH351Suspected of causing cancer
Precautionary statements: P203, P262, P264, P264 + P265, P270, P280, P301 + P316, P302 + P352, P305 + P351 + P338, P316, P318, P321, P330, P337 + P317, P361 + P364, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of N-Methyl-N-Nitroso p-Toluidine?
The CAS Registry Number of N-Methyl-N-Nitroso p-Toluidine is 937-24-6. It is also known as P-Toluidine, N-methyl-N-nitroso-, 4-Methyl-N-nitroso-N-methylaniline, N,4-dimethyl-N-nitrosoaniline.
What is the molecular formula and molecular weight of N-Methyl-N-Nitroso p-Toluidine?
N-Methyl-N-Nitroso p-Toluidine has the molecular formula C8H10N2O and a molecular weight of 150.18 g/mol. Its IUPAC name is N-methyl-N-(4-methylphenyl)nitrous amide.
What is N-Methyl-N-Nitroso p-Toluidine used for?
N-Methyl-N-Nitroso p-Toluidine is supplied as a characterised reference material related to Toluidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of N-Methyl-N-Nitroso p-Toluidine can I order?
We supply N-Methyl-N-Nitroso p-Toluidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with N-Methyl-N-Nitroso p-Toluidine?
Yes. Every lot of N-Methyl-N-Nitroso p-Toluidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can N-Methyl-N-Nitroso p-Toluidine be shipped internationally?
Yes. N-Methyl-N-Nitroso p-Toluidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
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