N-Methyl-N-tert-butyldimethylsilyltrifluoroac… 77377-52-7

Name: N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97%
Brand: Vaqora Chemicals
SKU: VQ-000912

About N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97%

N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide (CAS 77377-52-7) is a synthetic reagent offered by Vaqora Chemicals at a purity of 97%. Formula C9H18F3NOSi, molecular weight 241.33 g/mol. Its systematic (IUPAC) name is N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide. Alternative names: MTBSTFA+TBDMSCl and MTBSTFA + 1% TBDMSCl.

It is supplied as a liquid. Reported physical data include a density of 1.036 g/mL at 25 °C. Keep containers tightly closed in a cool, well-ventilated area away from heat and ignition sources. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Typical applications include organic synthesis, reaction development and medicinal chemistry. Our customers for this product work in academic and industrial research.

Vaqora Chemicals supplies N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide in 5 mL, 25 mL and 100 mL packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Organic synthesis
Reaction development
Medicinal chemistry

Industries

Specifications & identifiers

Chemical identifiers
Product name	N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97%
Catalogue No.	VQ-000912
CAS Number	77377-52-7
IUPAC name	N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
Molecular formula	C₉H₁₈F₃NOSi
Molecular weight	241.33 g/mol
Exact mass	241.111
Purity / assay	97%
HSN code	29399900
InChIKey	QRKUHYFDBWGLHJ-UHFFFAOYSA-N
SMILES	CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
PubChem CID	2724275

Physical properties
Physical form	Liquid
Appearance	Liquid
Density	1.036 g/mL at 25 °C
H-bond donors / acceptors	0 / 4
TPSA	20.3 Å²
Synonyms	MTBSTFA+TBDMSCl, N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide, MTBSTFA + 1% TBDMSCl, Silylating mixture VI, N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide, Acetamide, N-[(1,1-dimethylethyl)dimethylsilyl]-2,2,2-trifluoro-N-methyl-, Acetamide, N-((1,1-dimethylethyl)dimethylsilyl)-2,2,2-trifluoro-N-methyl-, n-(tert-butyldimethylsilyl)-n-methyl-trifluoroacetamide, N-(tert-butyldimethylsilyl)-2,2,2-trifluoro-N-methylacetamide, N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, n-(t-butyldimethylsilyl)-n-methyltrifluoroacetamide, n-methyl-n-(t-butyldimethylsilyl)trifluoroacetamide

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Warning

Hazard statements

H226Flammable liquid and vapor
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P261, P264, P264 + P265, P271, P280, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403 + P233, P403 + P235, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97%?

The CAS Registry Number of N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97% is 77377-52-7. It is also known as MTBSTFA+TBDMSCl, N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide, MTBSTFA + 1% TBDMSCl.

What is the molecular formula and molecular weight of N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97%?

N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97% has the molecular formula C9H18F3NOSi and a molecular weight of 241.33 g/mol. Its IUPAC name is N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide.

Which grade and pack sizes of N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97% can I order?

We supply N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97% in (97%) grade, in 5 mL, 25 mL, 100 mL packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97%?

Yes. Every lot of N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97% is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97% be shipped internationally?

Yes. N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, 97% is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.