N-Nitroso-4-hydroxypiperidine

Name: N-Nitroso-4-hydroxypiperidine
Brand: Vaqora Chemicals
SKU: VQ-023416

About N-Nitroso-4-hydroxypiperidine

Listed under CAS 55556-93-9, N-Nitroso-4-hydroxypiperidine is a nitrosamine impurity of Piperidine available from Vaqora Chemicals. With the molecular formula C5H10N2O2, it has a molar mass of 130.15 g/mol. Systematically, it is named 1-nitrosopiperidin-4-ol. Alternative names: N-Nitroso-4-Piperidinol and 1-Nitroso piperidin-4-ol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Piperidine, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitroso-4-hydroxypiperidine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Piperidine

View every impurity, metabolite and intermediate we list for Piperidine.

Piperidine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-4-hydroxypiperidine
Catalogue No.	VQ-023416
CAS Number	55556-93-9
IUPAC name	1-nitrosopiperidin-4-ol
Molecular formula	C₅H₁₀N₂O₂
Molecular weight	130.15 g/mol
Exact mass	130.0742
Grade	Reference Standard
HSN code	38229090
InChIKey	DLRQZSOHVPOGGS-UHFFFAOYSA-N
SMILES	C1CN(CCC1O)N=O
PubChem CID	41471

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	1 / 4
TPSA	52.9 Å²
Synonyms	N-Nitroso-4-Piperidinol, 1-Nitroso piperidin-4-ol, 1-Nitroso-4-piperidinol, 4-hydroxy-N-nitrosopiperidine, Nitrosopiperidinol, Nitroso-4-piperidinol, 4-Piperidinol, 1-nitroso-, 1-Nitroso-piperidin-4-ol, 1-Nitroso-4-piperidinol #, N-Nitroso-4-hydroxypiperidin

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H350May cause cancer
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-4-hydroxypiperidine?

The CAS Registry Number of N-Nitroso-4-hydroxypiperidine is 55556-93-9. It is also known as N-Nitroso-4-Piperidinol, 1-Nitroso piperidin-4-ol, 1-Nitroso-4-piperidinol.

What is the molecular formula and molecular weight of N-Nitroso-4-hydroxypiperidine?

N-Nitroso-4-hydroxypiperidine has the molecular formula C5H10N2O2 and a molecular weight of 130.15 g/mol. Its IUPAC name is 1-nitrosopiperidin-4-ol.

What is N-Nitroso-4-hydroxypiperidine used for?

N-Nitroso-4-hydroxypiperidine is supplied as a characterised reference material related to Piperidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-4-hydroxypiperidine can I order?

We supply N-Nitroso-4-hydroxypiperidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-4-hydroxypiperidine?

Yes. Every lot of N-Nitroso-4-hydroxypiperidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-4-hydroxypiperidine be shipped internationally?

Yes. N-Nitroso-4-hydroxypiperidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.