N-Nitroso Binimetinib
N-Nitroso Binimetinib – nitrosamine impurity reference standard, 93%. C17H14BrF2N5O4, MW 470.2. Order from Vaqora Chemicals with COA and global delivery.
About N-Nitroso Binimetinib
N-Nitroso Binimetinib is a nitrosamine impurity of Binimetinib from the Vaqora Chemicals catalogue with a typical assay of 93%. With the molecular formula C17H14BrF2N5O4, it has a molar mass of 470.2 g/mol. Systematically, it is named 6-(4-bromo-2-fluoro-N-nitrosoanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.
Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.
Typical applications
- Nitrosamine risk assessment
- Trace LC-MS/MS quantitation
- Method validation (AMV)
- Regulatory submissions
Industries
View every impurity, metabolite and intermediate we list for Binimetinib.
Binimetinib impuritiesSpecifications & identifiers
| Product name | N-Nitroso Binimetinib |
|---|---|
| Catalogue No. | VQ-006879 |
| IUPAC name | 6-(4-bromo-2-fluoro-N-nitrosoanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide |
| Molecular formula | C17H14BrF2N5O4 |
| Molecular weight | 470.2 g/mol |
| Exact mass | 469.0197 |
| Grade | Reference Standard |
| Purity / assay | 93% |
| HSN code | 38229090 |
| InChIKey | RSUXSVJPXGAHEC-UHFFFAOYSA-N |
| SMILES | CN1C=NC2=C1C=C(C(=C2F)N(C3=C(C=C(C=C3)Br)F)N=O)C(=O)NOCCO |
| PubChem CID | 169444912 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.4 |
| H-bond donors / acceptors | 2 / 9 |
| TPSA | 109 Ų |
Documents
Frequently asked questions
What is the molecular formula and molecular weight of N-Nitroso Binimetinib?
N-Nitroso Binimetinib has the molecular formula C17H14BrF2N5O4 and a molecular weight of 470.2 g/mol. Its IUPAC name is 6-(4-bromo-2-fluoro-N-nitrosoanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide.
What is N-Nitroso Binimetinib used for?
N-Nitroso Binimetinib is supplied as a characterised reference material related to Binimetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of N-Nitroso Binimetinib can I order?
We supply N-Nitroso Binimetinib in Reference Standard (93%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with N-Nitroso Binimetinib?
Yes. Every lot of N-Nitroso Binimetinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can N-Nitroso Binimetinib be shipped internationally?
Yes. We export N-Nitroso Binimetinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about N-Nitroso Binimetinib
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