N-Nitroso-Bisoprolol

Name: N-Nitroso-Bisoprolol
Brand: Vaqora Chemicals
SKU: VQ-006975

About N-Nitroso-Bisoprolol

N-Nitroso-Bisoprolol is a nitrosamine impurity of Bisoprolol carrying the CAS registry number 2820170-76-9, specified at 96.6% purity. Its molecular formula is C18H30N2O5 and its molecular weight is 354.4 g/mol. The IUPAC name is N-[2-hydroxy-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propyl]-N-propan-2-ylnitrous amide. Common synonyms include N-Nitroso Bisoprolol and N-Nitrosobisoprolol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Bisoprolol, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Nitroso-Bisoprolol is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Bisoprolol

View every impurity, metabolite and intermediate we list for Bisoprolol.

Bisoprolol impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-Bisoprolol
Catalogue No.	VQ-006975
CAS Number	2820170-76-9
IUPAC name	N-[2-hydroxy-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propyl]-N-propan-2-ylnitrous amide
Molecular formula	C₁₈H₃₀N₂O₅
Molecular weight	354.4 g/mol
Exact mass	354.2155
Grade	Reference Standard
Purity / assay	96.6%
HSN code	38229090
InChIKey	MEDUICQOPWENFS-UHFFFAOYSA-N
SMILES	CC(C)N(CC(COC1=CC=C(C=C1)COCCOC(C)C)O)N=O
PubChem CID	168480018

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 7
TPSA	80.6 Å²
Synonyms	N-(2-Hydroxy-3-(4-((2-isopropoxyethoxy)methyl)phenoxy)propyl)-N-isopropylnitrous amide, 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)nitrosoamino]-2-propanol, N-Nitroso Bisoprolol, N-Nitrosobisoprolol, N-Nitrosobisoprolol 0.1 mg/ml in Methanol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-Bisoprolol?

The CAS Registry Number of N-Nitroso-Bisoprolol is 2820170-76-9. It is also known as N-(2-Hydroxy-3-(4-((2-isopropoxyethoxy)methyl)phenoxy)propyl)-N-isopropylnitrous amide, 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)nitrosoamino]-2-propanol, N-Nitroso Bisoprolol.

What is the molecular formula and molecular weight of N-Nitroso-Bisoprolol?

N-Nitroso-Bisoprolol has the molecular formula C18H30N2O5 and a molecular weight of 354.4 g/mol. Its IUPAC name is N-[2-hydroxy-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propyl]-N-propan-2-ylnitrous amide.

What is N-Nitroso-Bisoprolol used for?

N-Nitroso-Bisoprolol is supplied as a characterised reference material related to Bisoprolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-Bisoprolol can I order?

We supply N-Nitroso-Bisoprolol in Reference Standard (96.6%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-Bisoprolol?

Yes. Every lot of N-Nitroso-Bisoprolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-Bisoprolol be shipped internationally?

Yes. We export N-Nitroso-Bisoprolol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.