N-Nitroso Bupropion

Name: N-Nitroso Bupropion
Brand: Vaqora Chemicals
SKU: VQ-021027

About N-Nitroso Bupropion

Vaqora Chemicals supplies N-Nitroso Bupropion, a nitrosamine impurity of Bupropion registered under CAS number 2763780-10-3. Formula C13H17ClN2O2, molecular weight 268.74 g/mol. Systematically, it is named N-tert-butyl-N-[1-(3-chlorophenyl)-1-oxopropan-2-yl]nitrous amide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Bupropion, method validation (AMV) and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Bupropion
Catalogue No.	VQ-021027
CAS Number	2763780-10-3
IUPAC name	N-tert-butyl-N-[1-(3-chlorophenyl)-1-oxopropan-2-yl]nitrous amide
Molecular formula	C₁₃H₁₇ClN₂O₂
Molecular weight	268.74 g/mol
Exact mass	268.0979
Grade	Reference Standard
HSN code	38229090
InChIKey	IPHMVIXBRCCXRJ-UHFFFAOYSA-N
SMILES	CC(C(=O)C1=CC(=CC=C1)Cl)N(C(C)(C)C)N=O
PubChem CID	165995445

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 4
TPSA	49.7 Å²
Synonyms	2-[tert-butyl(nitroso)amino]-1-(3-chlorophenyl)propan-1-one, 2-(tert-butyl(nitroso)amino)-1-(3-chlorophenyl)propan-1-one, 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)nitrosoamino]-1-propanone, 1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)nitrosoamino]-, N-(tert-butyl)-N-(1-(3-chlorophenyl)-1-oxopropan-2-yl)nitrous amide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H350May cause cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Bupropion?

The CAS Registry Number of N-Nitroso Bupropion is 2763780-10-3. It is also known as 2-[tert-butyl(nitroso)amino]-1-(3-chlorophenyl)propan-1-one, 2-(tert-butyl(nitroso)amino)-1-(3-chlorophenyl)propan-1-one, 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)nitrosoamino]-1-propanone.

What is the molecular formula and molecular weight of N-Nitroso Bupropion?

N-Nitroso Bupropion has the molecular formula C13H17ClN2O2 and a molecular weight of 268.74 g/mol. Its IUPAC name is N-tert-butyl-N-[1-(3-chlorophenyl)-1-oxopropan-2-yl]nitrous amide.

What is N-Nitroso Bupropion used for?

N-Nitroso Bupropion is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Bupropion can I order?

We supply N-Nitroso Bupropion in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Bupropion?

Yes. Every lot of N-Nitroso Bupropion is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Bupropion be shipped internationally?

Yes. N-Nitroso Bupropion is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.