N-Nitroso Chlordiazepoxide

Name: N-Nitroso Chlordiazepoxide
Brand: Vaqora Chemicals
SKU: VQ-044829

About N-Nitroso Chlordiazepoxide

Listed under CAS 51715-17-4, N-Nitroso Chlordiazepoxide is a nitrosamine impurity of Chlordiazepoxide available from Vaqora Chemicals. With the molecular formula C16H13ClN4O2, it has a molar mass of 328.75 g/mol. Its systematic (IUPAC) name is N-(7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)-N-methylnitrous amide. Common synonyms include Nitrosochlordiazepoxide and 2-N-nitrosochlordiazepoxide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 9 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso Chlordiazepoxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Chlordiazepoxide

View every impurity, metabolite and intermediate we list for Chlordiazepoxide.

Chlordiazepoxide impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Chlordiazepoxide
Catalogue No.	VQ-044829
CAS Number	51715-17-4
IUPAC name	N-(7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)-N-methylnitrous amide
Molecular formula	C₁₆H₁₃ClN₄O₂
Molecular weight	328.75 g/mol
Exact mass	328.0727
Grade	Reference Standard
HSN code	38229090
InChIKey	VGNMVQBFGJATJZ-UHFFFAOYSA-N
SMILES	CN(C1=NC2=C(C=C(C=C2)Cl)C(=[N+](C1)[O-])C3=CC=CC=C3)N=O
PubChem CID	40094

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	0 / 4
TPSA	73.8 Å²
Synonyms	Nitrosochlordiazepoxide, 2-N-nitrosochlordiazepoxide, NO-CDE, N-Nitrosochlorodiazepoxide, 7-chloro-2-[methyl(nitroso)amino]-5-phenyl-3H-1,4-benzodiazepin-4-ium-4-olate, 7-chloro-N-methyl-N-nitroso-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide, 7-Chloro-2-(1-methyl-2-oxohydrazino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide, N-(7-Chloro-4-oxo-5-phenyl-3H-1,4lambda~5~-benzodiazepin-2-yl)-N-methylnitrous amide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Chlordiazepoxide?

The CAS Registry Number of N-Nitroso Chlordiazepoxide is 51715-17-4. It is also known as Nitrosochlordiazepoxide, 2-N-nitrosochlordiazepoxide, NO-CDE.

What is the molecular formula and molecular weight of N-Nitroso Chlordiazepoxide?

N-Nitroso Chlordiazepoxide has the molecular formula C16H13ClN4O2 and a molecular weight of 328.75 g/mol. Its IUPAC name is N-(7-chloro-4-oxido-5-phenyl-3H-1,4-benzodiazepin-4-ium-2-yl)-N-methylnitrous amide.

What is N-Nitroso Chlordiazepoxide used for?

N-Nitroso Chlordiazepoxide is supplied as a characterised reference material related to Chlordiazepoxide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Chlordiazepoxide can I order?

We supply N-Nitroso Chlordiazepoxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Chlordiazepoxide?

Yes. Every lot of N-Nitroso Chlordiazepoxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Chlordiazepoxide be shipped internationally?

Yes. N-Nitroso Chlordiazepoxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.