N-Nitroso-Furosemide

Name: N-Nitroso-Furosemide
Brand: Vaqora Chemicals
SKU: VQ-030911

About N-Nitroso-Furosemide

N-Nitroso-Furosemide is a nitrosamine impurity of Furosemide carrying the CAS registry number 2708280-93-5. With the molecular formula C12H10ClN3O6S, it has a molar mass of 359.74 g/mol. The IUPAC name is 4-chloro-2-[furan-2-ylmethyl(nitroso)amino]-5-sulfamoylbenzoic acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitroso-Furosemide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Furosemide

View every impurity, metabolite and intermediate we list for Furosemide.

Furosemide impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso-Furosemide
Catalogue No.	VQ-030911
CAS Number	2708280-93-5
IUPAC name	4-chloro-2-[furan-2-ylmethyl(nitroso)amino]-5-sulfamoylbenzoic acid
Molecular formula	C₁₂H₁₀ClN₃O₆S
Molecular weight	359.74 g/mol
Exact mass	358.9979
Grade	Reference Standard
HSN code	38229090
InChIKey	SYQNRIYFBZMJSL-UHFFFAOYSA-N
SMILES	C1=COC(=C1)CN(C2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl)N=O
PubChem CID	162341886

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	2 / 9
TPSA	152 Å²

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H330Fatal if inhaled
H350May cause cancer
H372Causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P271, P273, P280, P284, P301 + P316, P304 + P340, P316, P318, P319, P320, P321, P330, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso-Furosemide?

The CAS Registry Number of N-Nitroso-Furosemide is 2708280-93-5. It is also known as 4-chloro-2-(furan-2-ylmethyl(nitroso)amino)-5-sulfamoylbenzoic acid, 4-chloro-2-((furan-2-ylmethyl)(nitroso)amino)-5-sulfamoylbenzoic acid, Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)nitrosoamino]-.

What is the molecular formula and molecular weight of N-Nitroso-Furosemide?

N-Nitroso-Furosemide has the molecular formula C12H10ClN3O6S and a molecular weight of 359.74 g/mol. Its IUPAC name is 4-chloro-2-[furan-2-ylmethyl(nitroso)amino]-5-sulfamoylbenzoic acid.

What is N-Nitroso-Furosemide used for?

N-Nitroso-Furosemide is supplied as a characterised reference material related to Furosemide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso-Furosemide can I order?

We supply N-Nitroso-Furosemide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso-Furosemide?

Yes. Every lot of N-Nitroso-Furosemide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso-Furosemide be shipped internationally?

Yes. N-Nitroso-Furosemide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.