N-Nitroso Itraconazole Impurity 1

Name: N-Nitroso Itraconazole Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-006909

About N-Nitroso Itraconazole Impurity 1

N-Nitroso Itraconazole Impurity 1 is a nitrosamine impurity of Itraconazole carrying the CAS registry number 75051-59-1, specified at 98% purity. With the molecular formula C11H15N3O2, it has a molar mass of 221.26 g/mol. Its systematic (IUPAC) name is 1-(4-methoxyphenyl)-4-nitrosopiperazine. It is also known as Posaconazole Nitroso Impurity 296.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso Itraconazole Impurity 1 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Itraconazole

View every impurity, metabolite and intermediate we list for Itraconazole.

Itraconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Itraconazole Impurity 1
Catalogue No.	VQ-006909
CAS Number	75051-59-1
IUPAC name	1-(4-methoxyphenyl)-4-nitrosopiperazine
Molecular formula	C₁₁H₁₅N₃O₂
Molecular weight	221.26 g/mol
Exact mass	221.1164
Grade	Reference Standard
Purity / assay	98%
HSN code	38229090
InChIKey	JOLPXZBXQHYGDW-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)N2CCN(CC2)N=O
PubChem CID	12952715

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	0 / 5
TPSA	45.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Itraconazole Impurity 1?

The CAS Registry Number of N-Nitroso Itraconazole Impurity 1 is 75051-59-1. It is also known as Posaconazole Nitroso Impurity 296.

What is the molecular formula and molecular weight of N-Nitroso Itraconazole Impurity 1?

N-Nitroso Itraconazole Impurity 1 has the molecular formula C11H15N3O2 and a molecular weight of 221.26 g/mol. Its IUPAC name is 1-(4-methoxyphenyl)-4-nitrosopiperazine.

What is N-Nitroso Itraconazole Impurity 1 used for?

N-Nitroso Itraconazole Impurity 1 is supplied as a characterised reference material related to Itraconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Itraconazole Impurity 1 can I order?

We supply N-Nitroso Itraconazole Impurity 1 in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Itraconazole Impurity 1?

Yes. Every lot of N-Nitroso Itraconazole Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Itraconazole Impurity 1 be shipped internationally?

Yes. We export N-Nitroso Itraconazole Impurity 1 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.