N-Nitroso Salbutamol

Name: N-Nitroso Salbutamol
Brand: Vaqora Chemicals
SKU: VQ-023727

About N-Nitroso Salbutamol

N-Nitroso Salbutamol is a nitrosamine impurity of Salbutamol carrying the CAS registry number 2919946-71-5. With the molecular formula C13H20N2O4, it has a molar mass of 268.31 g/mol. Systematically, it is named N-tert-butyl-N-[2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]nitrous amide. Common synonyms include N-nitroso-albuterol and N-Nitroso-Albuterol (N-Nitroso-Salbutamol).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitroso Salbutamol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Salbutamol

View every impurity, metabolite and intermediate we list for Salbutamol.

Salbutamol impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitroso Salbutamol
Catalogue No.	VQ-023727
CAS Number	2919946-71-5
IUPAC name	N-tert-butyl-N-[2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]nitrous amide
Molecular formula	C₁₃H₂₀N₂O₄
Molecular weight	268.31 g/mol
Exact mass	268.1423
Grade	Reference Standard
HSN code	38229090
InChIKey	ZMJPUQNSCRRRCS-UHFFFAOYSA-N
SMILES	CC(C)(C)N(CC(C1=CC(=C(C=C1)O)CO)O)N=O
PubChem CID	167719308

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	3 / 6
TPSA	93.4 Å²
Synonyms	4-{2-[tert-butyl(nitroso)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol, 4-(2-(tert-butyl(nitroso)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol, N-nitroso-albuterol, N-Nitroso-Albuterol (N-Nitroso-Salbutamol), 1,3-Benzenedimethanol, alpha1-[[(1,1-dimethylethyl)nitrosoamino]methyl]-4-hydroxy-, 2-(hydroxymethyl)-4-{1-hydroxy-2-[(2-methylprop-2-yl)(nitroso)amino]ethyl}phenol, N-(tert-butyl)-N-(2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)nitrous amide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H350May cause cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitroso Salbutamol?

The CAS Registry Number of N-Nitroso Salbutamol is 2919946-71-5. It is also known as 4-{2-[tert-butyl(nitroso)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol, 4-(2-(tert-butyl(nitroso)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol, N-nitroso-albuterol.

What is the molecular formula and molecular weight of N-Nitroso Salbutamol?

N-Nitroso Salbutamol has the molecular formula C13H20N2O4 and a molecular weight of 268.31 g/mol. Its IUPAC name is N-tert-butyl-N-[2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]nitrous amide.

What is N-Nitroso Salbutamol used for?

N-Nitroso Salbutamol is supplied as a characterised reference material related to Salbutamol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitroso Salbutamol can I order?

We supply N-Nitroso Salbutamol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitroso Salbutamol?

Yes. Every lot of N-Nitroso Salbutamol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitroso Salbutamol be shipped internationally?

Yes. N-Nitroso Salbutamol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.