N-Nitrosodihydrodibenzazepine

Name: N-Nitrosodihydrodibenzazepine
Brand: Vaqora Chemicals
SKU: VQ-021996

About N-Nitrosodihydrodibenzazepine

N-Nitrosodihydrodibenzazepine is a nitrosamine impurity of Carbamazepine carrying the CAS registry number 7458-08-4. With the molecular formula C14H12N2O, it has a molar mass of 224.26 g/mol. Its systematic (IUPAC) name is 11-nitroso-5,6-dihydrobenzo[b][1]benzazepine. Common synonyms include N-nitrosoiminodibenzyl and 10,11-Dihydro-5-nitroso-5H-dibenz(b,f)azepine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Carbamazepine, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer N-Nitrosodihydrodibenzazepine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Carbamazepine

View every impurity, metabolite and intermediate we list for Carbamazepine.

Carbamazepine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitrosodihydrodibenzazepine
Catalogue No.	VQ-021996
CAS Number	7458-08-4
IUPAC name	11-nitroso-5,6-dihydrobenzo[b][1]benzazepine
Molecular formula	C₁₄H₁₂N₂O
Molecular weight	224.26 g/mol
Exact mass	224.095
Grade	Reference Standard
HSN code	38229090
InChIKey	AVXDYTPASFOWQY-UHFFFAOYSA-N
SMILES	C1CC2=CC=CC=C2N(C3=CC=CC=C31)N=O
PubChem CID	81960

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	0 / 3
TPSA	32.7 Å²
Synonyms	5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine, N-nitrosoiminodibenzyl, 10,11-Dihydro-5-nitroso-5H-dibenz(b,f)azepine, N-nitroso-10,11-dihydro-5H-dibenz(b,f)azepine, N-Nitrosiminobibenzyl, 5-Nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine #, 5H-Dibenz[b,f]azepine, 10,11-dihydro-5-nitroso-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P321, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitrosodihydrodibenzazepine?

The CAS Registry Number of N-Nitrosodihydrodibenzazepine is 7458-08-4. It is also known as 5-nitroso-10,11-dihydro-5H-dibenzo[b,f]azepine, N-nitrosoiminodibenzyl, 10,11-Dihydro-5-nitroso-5H-dibenz(b,f)azepine.

What is the molecular formula and molecular weight of N-Nitrosodihydrodibenzazepine?

N-Nitrosodihydrodibenzazepine has the molecular formula C14H12N2O and a molecular weight of 224.26 g/mol. Its IUPAC name is 11-nitroso-5,6-dihydrobenzo[b][1]benzazepine.

What is N-Nitrosodihydrodibenzazepine used for?

N-Nitrosodihydrodibenzazepine is supplied as a characterised reference material related to Carbamazepine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitrosodihydrodibenzazepine can I order?

We supply N-Nitrosodihydrodibenzazepine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitrosodihydrodibenzazepine?

Yes. Every lot of N-Nitrosodihydrodibenzazepine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitrosodihydrodibenzazepine be shipped internationally?

Yes. N-Nitrosodihydrodibenzazepine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.