N-Nitrosopiperazine Palbociclib

Name: N-Nitrosopiperazine Palbociclib
Brand: Vaqora Chemicals
SKU: VQ-041308

About N-Nitrosopiperazine Palbociclib

N-Nitrosopiperazine Palbociclib (CAS 2955712-44-2) is a nitrosamine impurity of Palbociclib offered by Vaqora Chemicals. The compound has the formula C24H28N8O3, corresponding to a molecular weight of 476.5 g/mol. Systematically, it is named 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-nitrosopiperazin-1-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7-one. It is also known as N-Nitroso Palbociclib 1 or N-Nitrosopalbociclib.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-Nitrosopiperazine Palbociclib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Nitrosopiperazine Palbociclib
Catalogue No.	VQ-041308
CAS Number	2955712-44-2
IUPAC name	6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-nitrosopiperazin-1-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7-one
Molecular formula	C₂₄H₂₈N₈O₃
Molecular weight	476.5 g/mol
Exact mass	476.2284
Grade	Reference Standard
HSN code	38229090
InChIKey	BXUXPPSEBPSYOT-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)N=O)C5CCCC5)C(=O)C
PubChem CID	170910117

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 10
TPSA	124 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Nitrosopiperazine Palbociclib?

The CAS Registry Number of N-Nitrosopiperazine Palbociclib is 2955712-44-2. It is also known as N-Nitroso Palbociclib 1, N-Nitrosopalbociclib, Palbociclib Nitroso mpurity 158.

What is the molecular formula and molecular weight of N-Nitrosopiperazine Palbociclib?

N-Nitrosopiperazine Palbociclib has the molecular formula C24H28N8O3 and a molecular weight of 476.5 g/mol. Its IUPAC name is 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-nitrosopiperazin-1-yl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7-one.

What is N-Nitrosopiperazine Palbociclib used for?

N-Nitrosopiperazine Palbociclib is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Nitrosopiperazine Palbociclib can I order?

We supply N-Nitrosopiperazine Palbociclib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Nitrosopiperazine Palbociclib?

Yes. Every lot of N-Nitrosopiperazine Palbociclib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Nitrosopiperazine Palbociclib be shipped internationally?

Yes. We export N-Nitrosopiperazine Palbociclib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.