N-(S)-Glycidylphthalimide

Name: N-(S)-Glycidylphthalimide
Brand: Vaqora Chemicals
SKU: VQ-013612

About N-(S)-Glycidylphthalimide

Vaqora Chemicals supplies N-(S)-Glycidylphthalimide, a process intermediate or related compound of Rivaroxaban registered under CAS number 161596-47-0. The compound has the formula C11H9NO3, corresponding to a molecular weight of 203.19 g/mol. Systematically, it is named 2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione. It is also known as (S)-2-[(Oxiranyl)methyl]isoindole-1,3-dione or (S)-N-(2,3-Epoxypropan-1-yl)phthalimide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Rivaroxaban, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-(S)-Glycidylphthalimide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(S)-Glycidylphthalimide
Catalogue No.	VQ-013612
CAS Number	161596-47-0
IUPAC name	2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione
Molecular formula	C₁₁H₉NO₃
Molecular weight	203.19 g/mol
Exact mass	203.0582
Grade	Reference Standard
HSN code	2933
InChIKey	DUILGEYLVHGSEE-ZETCQYMHSA-N
SMILES	C1[C@@H](O1)CN2C(=O)C3=CC=CC=C3C2=O
PubChem CID	719412

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	0 / 3
TPSA	49.9 Å²
Synonyms	2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione, (S)-2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione, (S)-2-[(Oxiranyl)methyl]isoindole-1,3-dione, (S)-N-(2,3-Epoxypropan-1-yl)phthalimide, (S)-N-(2,3-Epoxypropyl)phthalimide, 2-[(S)-2-Oxiranylmethyl]-1H-isoindol-1,3(2H)-dione, N-((2S)-Oxiran-2-ylmethyl)phthalimide, (S)-(+)-N-(2,3-Epoxypropyl)phthalimide, 2-((2S)-2-Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione, (S)-N-Glycidylphthalimide, (S)-(+)-Glycidyl Phthalimide, (s)-glycidyl phthalimide

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H318Causes serious eye damage
H341Suspected of causing genetic defects

Precautionary statements: P203, P261, P264 + P265, P272, P280, P302 + P352, P305 + P354 + P338, P317, P318, P321, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 161596-47-0

(S)-N-Glycidylphthalimide, ≥99%

CAS: 161596-47-0
Formula: C₁₁H₉NO₃
MW: 203.19 g/mol

VQ-012547

Frequently asked questions

What is the CAS number of N-(S)-Glycidylphthalimide?

The CAS Registry Number of N-(S)-Glycidylphthalimide is 161596-47-0. It is also known as 2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione, (S)-2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione, (S)-2-[(Oxiranyl)methyl]isoindole-1,3-dione.

What is the molecular formula and molecular weight of N-(S)-Glycidylphthalimide?

N-(S)-Glycidylphthalimide has the molecular formula C11H9NO3 and a molecular weight of 203.19 g/mol. Its IUPAC name is 2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione.

What is N-(S)-Glycidylphthalimide used for?

N-(S)-Glycidylphthalimide is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(S)-Glycidylphthalimide can I order?

We supply N-(S)-Glycidylphthalimide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(S)-Glycidylphthalimide?

Yes. Every lot of N-(S)-Glycidylphthalimide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(S)-Glycidylphthalimide be shipped internationally?

Yes. N-(S)-Glycidylphthalimide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.