N-tert-Butoxycarbonyl-4-anilinopiperidine

Name: N-tert-Butoxycarbonyl-4-anilinopiperidine
Brand: Vaqora Chemicals
SKU: VQ-049259

About N-tert-Butoxycarbonyl-4-anilinopiperidine

Vaqora Chemicals supplies N-tert-Butoxycarbonyl-4-anilinopiperidine, an impurity of Niraparib registered under CAS number 125541-22-2. Its molecular formula is C16H24N2O2 and its molecular weight is 276.37 g/mol. The IUPAC name is tert-butyl 4-anilinopiperidine-1-carboxylate. Alternative names: 1-BOC-4-AP and 1-Boc-4-(Phenylamino)piperidine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Niraparib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-tert-Butoxycarbonyl-4-anilinopiperidine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Niraparib

View every impurity, metabolite and intermediate we list for Niraparib.

Niraparib impurities

Specifications & identifiers

Chemical identifiers
Product name	N-tert-Butoxycarbonyl-4-anilinopiperidine
Catalogue No.	VQ-049259
CAS Number	125541-22-2
IUPAC name	tert-butyl 4-anilinopiperidine-1-carboxylate
Molecular formula	C₁₆H₂₄N₂O₂
Molecular weight	276.37 g/mol
Exact mass	276.1838
Grade	Reference Standard
HSN code	38229090
InChIKey	HTIWISWAPVQGMI-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1CCC(CC1)NC2=CC=CC=C2
PubChem CID	1491502

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	1 / 3
TPSA	41.6 Å²
Synonyms	tert-butyl 4-(phenylamino)piperidine-1-carboxylate, 1-BOC-4-AP, 1-boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) and its salts, 1-Boc-4-(Phenylamino)piperidine, tert-butyl 4-(phenylamino)piperidinecarboxylate, 1-(tert-butoxycarbonyl)-4-phenylaminopiperidine, 1-Piperidinecarboxylic acid, 4-(phenylamino)-, 1,1-dimethylethyl ester, tert-butyl 4-anilinotetrahydro-1(2H)-pyridinecarboxylate, 4-ANBocP, 4-Anilino-1-Boc-piperidine, 4-Phenylamino-piperidine-1-carboxylic acid tert-butyl ester, 4-Phenylaminopiperidine-1-carboxylic acid tert-butyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-tert-Butoxycarbonyl-4-anilinopiperidine?

The CAS Registry Number of N-tert-Butoxycarbonyl-4-anilinopiperidine is 125541-22-2. It is also known as tert-butyl 4-(phenylamino)piperidine-1-carboxylate, 1-BOC-4-AP, 1-boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) and its salts.

What is the molecular formula and molecular weight of N-tert-Butoxycarbonyl-4-anilinopiperidine?

N-tert-Butoxycarbonyl-4-anilinopiperidine has the molecular formula C16H24N2O2 and a molecular weight of 276.37 g/mol. Its IUPAC name is tert-butyl 4-anilinopiperidine-1-carboxylate.

What is N-tert-Butoxycarbonyl-4-anilinopiperidine used for?

N-tert-Butoxycarbonyl-4-anilinopiperidine is supplied as a characterised reference material related to Niraparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-tert-Butoxycarbonyl-4-anilinopiperidine can I order?

We supply N-tert-Butoxycarbonyl-4-anilinopiperidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-tert-Butoxycarbonyl-4-anilinopiperidine?

Yes. Every lot of N-tert-Butoxycarbonyl-4-anilinopiperidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-tert-Butoxycarbonyl-4-anilinopiperidine be shipped internationally?

Yes. N-tert-Butoxycarbonyl-4-anilinopiperidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.