Naproxen Impurity A

Name: Naproxen Impurity A
Brand: Vaqora Chemicals
SKU: VQ-005314

About Naproxen Impurity A

Naproxen Impurity A is an impurity of Naproxen carrying the CAS registry number 52079-10-4 at a purity of 98.44%. Formula C13H12O3, molecular weight 216.23 g/mol. Systematically, it is named (2S)-2-(6-hydroxynaphthalen-2-yl)propanoic acid. It is also known as (S)-O-Desmethyl Naproxen or (S)-2-(6-Hydroxy-2-naphthyl)propionic Acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Naproxen to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Naproxen Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Naproxen

View every impurity, metabolite and intermediate we list for Naproxen.

Naproxen impurities

Specifications & identifiers

Chemical identifiers
Product name	Naproxen Impurity A
Catalogue No.	VQ-005314
CAS Number	52079-10-4
IUPAC name	(2S)-2-(6-hydroxynaphthalen-2-yl)propanoic acid
Molecular formula	C₁₃H₁₂O₃
Molecular weight	216.23 g/mol
Exact mass	216.0786
Grade	Reference Standard
Purity / assay	98.44%
HSN code	38229090
InChIKey	XWJUDDGELKXYNO-QMMMGPOBSA-N
SMILES	C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)O)C(=O)O
PubChem CID	13393711

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	(S)-O-Desmethyl Naproxen, (S)-2-(6-Hydroxy-2-naphthyl)propionic Acid, (S)-6-O-Desmethylnaproxen, (S)-6-Demethylnaproxen, O-Desmethylnaproxen, 6-O-Demethylnaproxen, Naproxen EP Impurity A, (S)-2-(6-Hydroxynaphthalen-2-yl)propanoic acid, (S)-6-Hydroxy-alpha-methyl-2-naphthaleneacetic acid, (S)-O-Desmethylnaproxen, (S)-6-Desmethyl Naproxen, (2S)-2-(6-Hydroxynaphthalen-2-yl)propanoic Acid (O-Demethylnaproxen)

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H400Very toxic to aquatic life

Precautionary statements: P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P321, P330, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naproxen Impurity A?

The CAS Registry Number of Naproxen Impurity A is 52079-10-4. It is also known as (S)-O-Desmethyl Naproxen, (S)-2-(6-Hydroxy-2-naphthyl)propionic Acid, (S)-6-O-Desmethylnaproxen.

What is the molecular formula and molecular weight of Naproxen Impurity A?

Naproxen Impurity A has the molecular formula C13H12O3 and a molecular weight of 216.23 g/mol. Its IUPAC name is (2S)-2-(6-hydroxynaphthalen-2-yl)propanoic acid.

What is Naproxen Impurity A used for?

Naproxen Impurity A is supplied as a characterised reference material related to Naproxen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naproxen Impurity A can I order?

We supply Naproxen Impurity A in Reference Standard (98.44%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naproxen Impurity A?

Yes. Every lot of Naproxen Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naproxen Impurity A be shipped internationally?

Yes. Naproxen Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.