Nepafenac Impurity B

Name: Nepafenac Impurity B
Brand: Vaqora Chemicals
SKU: VQ-023227

About Nepafenac Impurity B

Vaqora Chemicals supplies Nepafenac Impurity B, an impurity of Nepafenac registered under CAS number 78281-61-5. Formula C16H16N2O2S, molecular weight 300.4 g/mol. Systematically, it is named 2-(2-amino-3-benzoylphenyl)-2-methylsulfanylacetamide. Alternative names: Nepafenac Methylthio Impurity.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Nepafenac to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nepafenac Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nepafenac

View every impurity, metabolite and intermediate we list for Nepafenac.

Nepafenac impurities

Specifications & identifiers

Chemical identifiers
Product name	Nepafenac Impurity B
Catalogue No.	VQ-023227
CAS Number	78281-61-5
IUPAC name	2-(2-amino-3-benzoylphenyl)-2-methylsulfanylacetamide
Molecular formula	C₁₆H₁₆N₂O₂S
Molecular weight	300.4 g/mol
Exact mass	300.0932
Grade	Reference Standard
HSN code	38229090
InChIKey	FPRGALQPEHLMNK-UHFFFAOYSA-N
SMILES	CSC(C1=C(C(=CC=C1)C(=O)C2=CC=CC=C2)N)C(=O)N
PubChem CID	15634727

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 4
TPSA	111 Å²
Synonyms	2-(2-Amino-3-benzoylphenyl)-2-(methylthio)acetamide, Nepafenac Methylthio Impurity, 2-Amino-3-benzoyl-alpha-(methylthio)benzeneacetamide, 2-Amino-3-benzoyl-a-methylthio-phenylacetamide, 2-amino-3-benzoly-a-methylthio-phenylacetamide, 2-(2-amino-3-benzoyl-phenyl)-2-methylsulfanyl-acetamide, 2-Amino-3-benzoyl-alpha-(methylthio)phenylacetamide, 2-amino-3-benzoyl-alpha-(methylthio)-phenylacetamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P301 + P317, P304 + P340, P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nepafenac Impurity B?

The CAS Registry Number of Nepafenac Impurity B is 78281-61-5. It is also known as 2-(2-Amino-3-benzoylphenyl)-2-(methylthio)acetamide, Nepafenac Methylthio Impurity, 2-Amino-3-benzoyl-alpha-(methylthio)benzeneacetamide.

What is the molecular formula and molecular weight of Nepafenac Impurity B?

Nepafenac Impurity B has the molecular formula C16H16N2O2S and a molecular weight of 300.4 g/mol. Its IUPAC name is 2-(2-amino-3-benzoylphenyl)-2-methylsulfanylacetamide.

What is Nepafenac Impurity B used for?

Nepafenac Impurity B is supplied as a characterised reference material related to Nepafenac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nepafenac Impurity B can I order?

We supply Nepafenac Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nepafenac Impurity B?

Yes. Every lot of Nepafenac Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nepafenac Impurity B be shipped internationally?

Yes. Nepafenac Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.