Nilotinib

Name: Nilotinib
Brand: Vaqora Chemicals
SKU: VQ-007612

About Nilotinib

Nilotinib (CAS 641571-10-0) is a high-purity reference standard of Nilotinib offered by Vaqora Chemicals. Its molecular formula is C28H22F3N7O and its molecular weight is 529.5 g/mol. Alternative names: Tasigna and AMN 107.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Nilotinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib
Catalogue No.	VQ-007612
CAS Number	641571-10-0
Other CAS	923288-95-3, 923288-90-8
IUPAC name	4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Molecular formula	C₂₈H₂₂F₃N₇O
Molecular weight	529.5 g/mol
Exact mass	529.1838
Grade	Reference Standard
HSN code	38229090
InChIKey	HHZIURLSWUIHRB-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
PubChem CID	644241

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	2 / 9
TPSA	97.6 Å²
Synonyms	Tasigna, AMN 107, AMN-107, AMN 107 Base, Nilotinib (AMN-107), Nilotinib free base, 641571-10-0 (free base), Nilotinib (Standard), 3gp0, AMN 107 Base Form, Nilotinib (USAN/INN), Nilotinib - Bio-X trade mark

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P264, P270, P273, P280, P318, P319, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib?

The CAS Registry Number of Nilotinib is 641571-10-0. It is also known as Tasigna, AMN 107, AMN-107.

What is the molecular formula and molecular weight of Nilotinib?

Nilotinib has the molecular formula C28H22F3N7O and a molecular weight of 529.5 g/mol. Its IUPAC name is 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide.

What is Nilotinib used for?

Nilotinib is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib can I order?

We supply Nilotinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib?

Yes. Every lot of Nilotinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib be shipped internationally?

Yes. Nilotinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.