Nilotinib Impurity 18

Name: Nilotinib Impurity 18
Brand: Vaqora Chemicals
SKU: VQ-005360

About Nilotinib Impurity 18

Listed under CAS 2469039-94-7, Nilotinib Impurity 18 is an impurity of Nilotinib available from Vaqora Chemicals, specified at 94% purity. Formula C28H21ClF3N7O, molecular weight 564.0 g/mol. Common synonyms include Nilotinib Chloro Impurity.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Nilotinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib Impurity 18
Catalogue No.	VQ-005360
CAS Number	2469039-94-7
IUPAC name	3-[(5-chloro-4-pyridin-3-ylpyrimidin-2-yl)amino]-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide
Molecular formula	C₂₈H₂₁ClF₃N₇O
Molecular weight	564 g/mol
Exact mass	563.1448
Grade	Reference Standard
Purity / assay	94%
HSN code	38229090
InChIKey	KGPBKNJEPLSFIW-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=C(C(=N4)C5=CN=CC=C5)Cl
PubChem CID	145875085

Physical properties
Physical form	Solid
LogP (XLogP3)	5.5
H-bond donors / acceptors	2 / 9
TPSA	97.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib Impurity 18?

The CAS Registry Number of Nilotinib Impurity 18 is 2469039-94-7. It is also known as Nilotinib Chloro Impurity.

What is the molecular formula and molecular weight of Nilotinib Impurity 18?

Nilotinib Impurity 18 has the molecular formula C28H21ClF3N7O and a molecular weight of 564 g/mol. Its IUPAC name is 3-[(5-chloro-4-pyridin-3-ylpyrimidin-2-yl)amino]-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide.

What is Nilotinib Impurity 18 used for?

Nilotinib Impurity 18 is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib Impurity 18 can I order?

We supply Nilotinib Impurity 18 in Reference Standard (94%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib Impurity 18?

Yes. Every lot of Nilotinib Impurity 18 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib Impurity 18 be shipped internationally?

Yes. We export Nilotinib Impurity 18 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.