Nilotinib Impurity H

Name: Nilotinib Impurity H
Brand: Vaqora Chemicals
SKU: VQ-005370

About Nilotinib Impurity H

Listed under CAS 641571-15-5, Nilotinib Impurity H is an impurity of Nilotinib available from Vaqora Chemicals at a purity of 15.32%. The compound has the formula C28H22F3N7O, corresponding to a molecular weight of 529.5 g/mol. Alternative names: Nilotinib Regio Isomer and Nilotinib Impurity 9.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Nilotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib Impurity H
Catalogue No.	VQ-005370
CAS Number	641571-15-5
IUPAC name	4-methyl-N-[3-(5-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Molecular formula	C₂₈H₂₂F₃N₇O
Molecular weight	529.5 g/mol
Exact mass	529.1838
Grade	Reference Standard
Purity / assay	15.32%
HSN code	38229090
InChIKey	LVVDYLLEWIHKDY-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=NC=C3C)NC4=NC=CC(=N4)C5=CN=CC=C5
PubChem CID	11180078

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	2 / 9
TPSA	97.6 Å²
Synonyms	Nilotinib Regio Isomer, Nilotinib Impurity 9, Nilotinib EP Impurity H, Nilotinib Impurity 6, NilotinibImpurity H, Nilotinib Impurity04, Nilotinib Hydrochloride Monohydrate EP Impurity H, Nilotinib Impurity 13 (Nilotinib EP Impurity H)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib Impurity H?

The CAS Registry Number of Nilotinib Impurity H is 641571-15-5. It is also known as Nilotinib Regio Isomer, Nilotinib Impurity 9, Nilotinib EP Impurity H.

What is the molecular formula and molecular weight of Nilotinib Impurity H?

Nilotinib Impurity H has the molecular formula C28H22F3N7O and a molecular weight of 529.5 g/mol. Its IUPAC name is 4-methyl-N-[3-(5-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide.

What is Nilotinib Impurity H used for?

Nilotinib Impurity H is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib Impurity H can I order?

We supply Nilotinib Impurity H in Reference Standard (15.32%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib Impurity H?

Yes. Every lot of Nilotinib Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib Impurity H be shipped internationally?

Yes. We export Nilotinib Impurity H worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.