Niraparib Carboxylic Acid

Name: Niraparib Carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-026926

About Niraparib Carboxylic Acid

Vaqora Chemicals supplies Niraparib Carboxylic Acid, an impurity of Niraparib registered under CAS number 1476777-06-6. With the molecular formula C19H19N3O2, it has a molar mass of 321.4 g/mol. The IUPAC name is 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxylic acid. Common synonyms include Niraparib metabolite M1.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Niraparib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Niraparib Carboxylic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Niraparib

View every impurity, metabolite and intermediate we list for Niraparib.

Niraparib impurities

Specifications & identifiers

Chemical identifiers
Product name	Niraparib Carboxylic Acid
Catalogue No.	VQ-026926
CAS Number	1476777-06-6
IUPAC name	2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxylic acid
Molecular formula	C₁₉H₁₉N₃O₂
Molecular weight	321.4 g/mol
Exact mass	321.1477
Grade	Reference Standard
HSN code	38229090
InChIKey	HDQHGRLURKGIFL-CQSZACIVSA-N
SMILES	C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)O
PubChem CID	118737587

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	2 / 4
TPSA	67.2 Å²
Synonyms	Niraparib metabolite M1, (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxylic acid, 2H-Indazole-7-carboxylic acid, 2-(4-(3S)-3-piperidinylphenyl)-, 2H-Indazole-7-carboxylic acid, 2-[4-(3S)-3-piperidinylphenyl]-, 2-[4-[(3S)-3-piperidyl]phenyl]indazole-7-carboxylic acid, 2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxylic acid, 2-[4-[(3s)-piperidine-3-yl]phenyl]indazole-7-carboxylic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Niraparib Carboxylic Acid?

The CAS Registry Number of Niraparib Carboxylic Acid is 1476777-06-6. It is also known as Niraparib metabolite M1, (S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxylic acid, 2H-Indazole-7-carboxylic acid, 2-(4-(3S)-3-piperidinylphenyl)-.

What is the molecular formula and molecular weight of Niraparib Carboxylic Acid?

Niraparib Carboxylic Acid has the molecular formula C19H19N3O2 and a molecular weight of 321.4 g/mol. Its IUPAC name is 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxylic acid.

What is Niraparib Carboxylic Acid used for?

Niraparib Carboxylic Acid is supplied as a characterised reference material related to Niraparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Niraparib Carboxylic Acid can I order?

We supply Niraparib Carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Niraparib Carboxylic Acid?

Yes. Every lot of Niraparib Carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Niraparib Carboxylic Acid be shipped internationally?

Yes. We export Niraparib Carboxylic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.