Nitrosocarbamylcyanomethane

Name: Nitrosocarbamylcyanomethane
Brand: Vaqora Chemicals
SKU: VQ-049063

About Nitrosocarbamylcyanomethane

Vaqora Chemicals supplies Nitrosocarbamylcyanomethane, a nitrosamine impurity of Metformin registered under CAS number 83252-78-2. Formula C3H3N3O2, molecular weight 113.08 g/mol. Its systematic (IUPAC) name is 2-cyano-2-nitrosoacetamide. It is also known as Acetamide, 2-cyano-2-nitroso- or 2-cyano-2-nitroso-acetamide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Metformin, method validation (AMV) and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nitrosocarbamylcyanomethane is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Metformin

View every impurity, metabolite and intermediate we list for Metformin.

Metformin impurities

Specifications & identifiers

Chemical identifiers
Product name	Nitrosocarbamylcyanomethane
Catalogue No.	VQ-049063
CAS Number	83252-78-2
IUPAC name	2-cyano-2-nitrosoacetamide
Molecular formula	C₃H₃N₃O₂
Molecular weight	113.08 g/mol
Exact mass	113.0225
Grade	Reference Standard
HSN code	38229090
InChIKey	DXISQUITOXALCU-UHFFFAOYSA-N
SMILES	C(#N)C(C(=O)N)N=O
PubChem CID	385985

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.3
H-bond donors / acceptors	1 / 4
TPSA	96.3 Å²

Safety & hazard information (GHS)

Corrosive

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H318Causes serious eye damage

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P316, P305 + P354 + P338, P317, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nitrosocarbamylcyanomethane?

The CAS Registry Number of Nitrosocarbamylcyanomethane is 83252-78-2. It is also known as Acetamide, 2-cyano-2-nitroso-, 2-cyano-2-nitroso-acetamide, 3-Nitrilo-N~2~-oxoalaninamide.

What is the molecular formula and molecular weight of Nitrosocarbamylcyanomethane?

Nitrosocarbamylcyanomethane has the molecular formula C3H3N3O2 and a molecular weight of 113.08 g/mol. Its IUPAC name is 2-cyano-2-nitrosoacetamide.

What is Nitrosocarbamylcyanomethane used for?

Nitrosocarbamylcyanomethane is supplied as a characterised reference material related to Metformin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nitrosocarbamylcyanomethane can I order?

We supply Nitrosocarbamylcyanomethane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nitrosocarbamylcyanomethane?

Yes. Every lot of Nitrosocarbamylcyanomethane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nitrosocarbamylcyanomethane be shipped internationally?

Yes. Nitrosocarbamylcyanomethane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.