N,O-Bis(trimethylsilyl)trifluoroacetamide

Name: N,O-Bis(trimethylsilyl)trifluoroacetamide
Brand: Vaqora Chemicals
SKU: VQ-011130

About N,O-Bis(trimethylsilyl)trifluoroacetamide

N,O-Bis(trimethylsilyl)trifluoroacetamide (CAS 25561-30-2) is an organosilicon compound offered by Vaqora Chemicals. Its molecular formula is C8H18F3NOSi2 and its molecular weight is 257.4 g/mol. Systematically, it is named trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate. Common synonyms include Bis(trimethylsilyl)trifluoroacetamide and BSTFA.

Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Key uses span organic synthesis and API synthesis. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N,O-Bis(trimethylsilyl)trifluoroacetamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch. SDS and detailed specification sheets can be requested with your quotation. Custom pack sizes, bulk quantities and specific analytical data can be arranged on request.

Typical applications

Organic synthesis
API synthesis

Industries

Specifications & identifiers

Chemical identifiers
Product name	N,O-Bis(trimethylsilyl)trifluoroacetamide
Catalogue No.	VQ-011130
CAS Number	25561-30-2
IUPAC name	trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate
Molecular formula	C₈H₁₈F₃NOSi₂
Molecular weight	257.4 g/mol
Exact mass	257.0879
Grade	Reference Standard
InChIKey	XCOBLONWWXQEBS-UHFFFAOYSA-N
SMILES	C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C
PubChem CID	94358

Physical properties
Physical form	Other
H-bond donors / acceptors	0 / 5
TPSA	21.6 Å²
Synonyms	Bis(trimethylsilyl)trifluoroacetamide, 2,2,2-Trifluoro-N,O-bis(trimethylsilyl)acetamide, 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate Trimethylsilanol, BSTFA, N,O-Bis(trimethylsilyl)trifluoroacetamide, Trifluoro-N,O-bis(trimethylsilyl)acetamide, Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate, N,O-bis(TMS)3FAN, Ethanimidic acid, 2,2,2-trifluoro-N-(trimethylsilyl)-, trimethylsilyl ester, N,O-bis-(TRIMETHYLSILYL)-TRIFLUOROACETAMIDE, N,O-Bis(trimethylsilyl)trifluoroacetamide (~90%), C8H18F3NOSi2

Safety & hazard information (GHS)

Flammable

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H226Flammable liquid and vapor
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P319, P321, P332 + P317, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 25561-30-2

Puriss

N,O-Bis(trimethylsilyl)trifluoroacetamide, 98%

CAS: 25561-30-2
Formula: C₈H₁₈F₃NOSi₂
MW: 257.4 g/mol

VQ-000903

AR

N,O-Bis(trimethylsilyl)trifluoroacetamide, AR >98%

CAS: 25561-30-2
Formula: C₈H₁₈F₃NOSi₂
MW: 257.4 g/mol

VQ-045825

Frequently asked questions

What is the CAS number of N,O-Bis(trimethylsilyl)trifluoroacetamide?

The CAS Registry Number of N,O-Bis(trimethylsilyl)trifluoroacetamide is 25561-30-2. It is also known as Bis(trimethylsilyl)trifluoroacetamide, 2,2,2-Trifluoro-N,O-bis(trimethylsilyl)acetamide, 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate Trimethylsilanol.

What is the molecular formula and molecular weight of N,O-Bis(trimethylsilyl)trifluoroacetamide?

N,O-Bis(trimethylsilyl)trifluoroacetamide has the molecular formula C8H18F3NOSi2 and a molecular weight of 257.4 g/mol. Its IUPAC name is trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate.

Which grade and pack sizes of N,O-Bis(trimethylsilyl)trifluoroacetamide can I order?

We supply N,O-Bis(trimethylsilyl)trifluoroacetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N,O-Bis(trimethylsilyl)trifluoroacetamide?

Yes. Every lot of N,O-Bis(trimethylsilyl)trifluoroacetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N,O-Bis(trimethylsilyl)trifluoroacetamide be shipped internationally?

Yes. N,O-Bis(trimethylsilyl)trifluoroacetamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.