Norketotifen

Name: Norketotifen
Brand: Vaqora Chemicals
SKU: VQ-037821

About Norketotifen

Vaqora Chemicals supplies Norketotifen, an impurity of Ketotifen registered under CAS number 34580-20-6. The compound has the formula C18H17NOS, corresponding to a molecular weight of 295.4 g/mol. Systematically, it is named 2-piperidin-4-ylidene-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one. Alternative names: N-Desmethylketotifen and GNF-Pf-187.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Ketotifen to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ketotifen

View every impurity, metabolite and intermediate we list for Ketotifen.

Ketotifen impurities

Specifications & identifiers

Chemical identifiers
Product name	Norketotifen
Catalogue No.	VQ-037821
CAS Number	34580-20-6
IUPAC name	2-piperidin-4-ylidene-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one
Molecular formula	C₁₈H₁₇NOS
Molecular weight	295.4 g/mol
Exact mass	295.1031
Grade	Reference Standard
HSN code	38229090
InChIKey	IYSYPCSSDZBWHN-UHFFFAOYSA-N
SMILES	C1CNCCC1=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3
PubChem CID	9904236

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 3
TPSA	57.3 Å²
Synonyms	N-Desmethylketotifen, 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(4-piperidinylidene)-, 4,9-Dihydro-4-(4-piperidinylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4-(piperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one, GNF-Pf-187, 4-Piperidin-4-ylidene-4,9-dihydro-1-thia-benzo[f]azulen-10-one, 4-(4-piperidinylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one, 2-(4-piperidylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Norketotifen?

The CAS Registry Number of Norketotifen is 34580-20-6. It is also known as N-Desmethylketotifen, 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(4-piperidinylidene)-, 4,9-Dihydro-4-(4-piperidinylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one.

What is the molecular formula and molecular weight of Norketotifen?

Norketotifen has the molecular formula C18H17NOS and a molecular weight of 295.4 g/mol. Its IUPAC name is 2-piperidin-4-ylidene-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one.

What is Norketotifen used for?

Norketotifen is supplied as a characterised reference material related to Ketotifen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Norketotifen can I order?

We supply Norketotifen in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Norketotifen?

Yes. Every lot of Norketotifen is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Norketotifen be shipped internationally?

Yes. Norketotifen is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.