O-Demethyl Lenvatinib

Name: O-Demethyl Lenvatinib
Brand: Vaqora Chemicals
SKU: VQ-026401

About O-Demethyl Lenvatinib

Listed under CAS 417717-04-5, O-Demethyl Lenvatinib is a metabolite or degradation product of Lenvatinib available from Vaqora Chemicals. With the molecular formula C20H17ClN4O4, it has a molar mass of 412.8 g/mol. Its systematic (IUPAC) name is 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-hydroxyquinoline-6-carboxamide. It is also known as O-Desmethyl Lenvatinib or Lenvatinib metabolite M2.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Lenvatinib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, O-Demethyl Lenvatinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Lenvatinib

View every impurity, metabolite and intermediate we list for Lenvatinib.

Lenvatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Demethyl Lenvatinib
Catalogue No.	VQ-026401
CAS Number	417717-04-5
IUPAC name	4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-hydroxyquinoline-6-carboxamide
Molecular formula	C₂₀H₁₇ClN₄O₄
Molecular weight	412.8 g/mol
Exact mass	412.0938
Grade	Reference Standard
HSN code	38229090
InChIKey	XEZZOIWZFIDBIQ-UHFFFAOYSA-N
SMILES	C1CC1NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)O)C(=O)N)Cl
PubChem CID	135566046

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	4 / 5
TPSA	127 Å²
Synonyms	O-Desmethyl Lenvatinib, Lenvatinib metabolite M2, 4-(3-chloro-4-(((cyclopropylamino)carbonyl)amino)phenoxy)-7-hydroxy-6-quinolinecarboxamide, 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-hydroxy-6-quinolinecarboxamide, 4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-hydroxyquinoline-6-carboxamide, 4-[3-Chloro-4-(cyclopropylcarbamamido)phenoxy]-7-hydroxy-6-quinolinecarboxamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Demethyl Lenvatinib?

The CAS Registry Number of O-Demethyl Lenvatinib is 417717-04-5. It is also known as O-Desmethyl Lenvatinib, Lenvatinib metabolite M2, 4-(3-chloro-4-(((cyclopropylamino)carbonyl)amino)phenoxy)-7-hydroxy-6-quinolinecarboxamide.

What is the molecular formula and molecular weight of O-Demethyl Lenvatinib?

O-Demethyl Lenvatinib has the molecular formula C20H17ClN4O4 and a molecular weight of 412.8 g/mol. Its IUPAC name is 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-hydroxyquinoline-6-carboxamide.

What is O-Demethyl Lenvatinib used for?

O-Demethyl Lenvatinib is supplied as a characterised reference material related to Lenvatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Demethyl Lenvatinib can I order?

We supply O-Demethyl Lenvatinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Demethyl Lenvatinib?

Yes. Every lot of O-Demethyl Lenvatinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Demethyl Lenvatinib be shipped internationally?

Yes. We export O-Demethyl Lenvatinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.