Olanzapine N-Desmethyl Impurity

Name: Olanzapine N-Desmethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-007212

About Olanzapine N-Desmethyl Impurity

Vaqora Chemicals supplies Olanzapine N-Desmethyl Impurity, a metabolite or degradation product of Olanzapine registered under CAS number 161696-76-0 with a typical assay of 98%. Formula C16H18N4S, molecular weight 298.4 g/mol. The IUPAC name is 2-methyl-4-piperazin-1-yl-10H-thieno[2,3-b][1,5]benzodiazepine. It is also known as N-Desmethyl Olanzapine or 4'-Desmethylolanzapine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Olanzapine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Olanzapine N-Desmethyl Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Olanzapine

View every impurity, metabolite and intermediate we list for Olanzapine.

Olanzapine impurities

Specifications & identifiers

Chemical identifiers
Product name	Olanzapine N-Desmethyl Impurity
Catalogue No.	VQ-007212
CAS Number	161696-76-0
IUPAC name	2-methyl-4-piperazin-1-yl-10H-thieno[2,3-b][1,5]benzodiazepine
Molecular formula	C₁₆H₁₈N₄S
Molecular weight	298.4 g/mol
Exact mass	298.1252
Grade	Reference Standard
Purity / assay	98%
HSN code	38229090
InChIKey	FHPIXVHJEIZKJW-UHFFFAOYSA-N
SMILES	CC1=CC2=C(S1)NC3=CC=CC=C3N=C2N4CCNCC4
PubChem CID	135446209

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 4
TPSA	67.9 Å²
Synonyms	N-Desmethyl Olanzapine, 2-methyl-4-(1-piperazinyl)-10H-Thieno[2,3-b][1,5]benzodiazepine, 4'-Desmethylolanzapine, Desmethylolanzapine, N-Demethylolanzapine, N-Desmethylolanzapine, N-desmethyl-olanzapine, 10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-methyl-4-(1-piperazinyl)-, 10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl)-, N-Demethyl Olanzapine, 2-Methyl-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine, olanzapine n-desmethyl metabolite

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Olanzapine N-Desmethyl Impurity?

The CAS Registry Number of Olanzapine N-Desmethyl Impurity is 161696-76-0. It is also known as N-Desmethyl Olanzapine, 2-methyl-4-(1-piperazinyl)-10H-Thieno[2,3-b][1,5]benzodiazepine, 4'-Desmethylolanzapine.

What is the molecular formula and molecular weight of Olanzapine N-Desmethyl Impurity?

Olanzapine N-Desmethyl Impurity has the molecular formula C16H18N4S and a molecular weight of 298.4 g/mol. Its IUPAC name is 2-methyl-4-piperazin-1-yl-10H-thieno[2,3-b][1,5]benzodiazepine.

What is Olanzapine N-Desmethyl Impurity used for?

Olanzapine N-Desmethyl Impurity is supplied as a characterised reference material related to Olanzapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Olanzapine N-Desmethyl Impurity can I order?

We supply Olanzapine N-Desmethyl Impurity in Reference Standard (98%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Olanzapine N-Desmethyl Impurity?

Yes. Every lot of Olanzapine N-Desmethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Olanzapine N-Desmethyl Impurity be shipped internationally?

Yes. Olanzapine N-Desmethyl Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.