Olaparib Nitroso Impurity 1

Name: Olaparib Nitroso Impurity 1
Brand: Vaqora Chemicals
SKU: VQ-007015

About Olaparib Nitroso Impurity 1

Vaqora Chemicals supplies Olaparib Nitroso Impurity 1, a nitrosamine impurity of Olaparib registered under CAS number 2742659-74-9. With the molecular formula C20H18FN5O3, it has a molar mass of 395.4 g/mol. The IUPAC name is 4-[[4-fluoro-3-(4-nitrosopiperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Olaparib Nitroso Impurity 1 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Olaparib

View every impurity, metabolite and intermediate we list for Olaparib.

Olaparib impurities

Specifications & identifiers

Chemical identifiers
Product name	Olaparib Nitroso Impurity 1
Catalogue No.	VQ-007015
CAS Number	2742659-74-9
IUPAC name	4-[[4-fluoro-3-(4-nitrosopiperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
Molecular formula	C₂₀H₁₈FN₅O₃
Molecular weight	395.4 g/mol
Exact mass	395.1394
Grade	Reference Standard
HSN code	38229090
InChIKey	NDRFMKMMSQXHML-UHFFFAOYSA-N
SMILES	C1CN(CCN1C(=O)C2=C(C=CC(=C2)CC3=NNC(=O)C4=CC=CC=C43)F)N=O
PubChem CID	165711920

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 7
TPSA	94.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Olaparib Nitroso Impurity 1?

The CAS Registry Number of Olaparib Nitroso Impurity 1 is 2742659-74-9. It is also known as 4-[[4-Fluoro-3-[(4-nitroso-1-piperazinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinone, 4-(4-Fluoro-3-(4-nitrosopiperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one, N-Nitroso N-Descyclopropanecarbaldehyde Olaparib.

What is the molecular formula and molecular weight of Olaparib Nitroso Impurity 1?

Olaparib Nitroso Impurity 1 has the molecular formula C20H18FN5O3 and a molecular weight of 395.4 g/mol. Its IUPAC name is 4-[[4-fluoro-3-(4-nitrosopiperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one.

What is Olaparib Nitroso Impurity 1 used for?

Olaparib Nitroso Impurity 1 is supplied as a characterised reference material related to Olaparib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Olaparib Nitroso Impurity 1 can I order?

We supply Olaparib Nitroso Impurity 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Olaparib Nitroso Impurity 1?

Yes. Every lot of Olaparib Nitroso Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Olaparib Nitroso Impurity 1 be shipped internationally?

Yes. We export Olaparib Nitroso Impurity 1 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.