Olopatadine

Name: Olopatadine
Brand: Vaqora Chemicals
SKU: VQ-007628

About Olopatadine

Listed under CAS 113806-05-6, Olopatadine is a high-purity reference standard of Olopatadine available from Vaqora Chemicals. Formula C21H23NO3, molecular weight 337.4 g/mol. The IUPAC name is 2-[(11Z)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid. Common synonyms include Opatanol and AL-4943A.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Olopatadine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Olopatadine

View every impurity, metabolite and intermediate we list for Olopatadine.

Olopatadine impurities

Specifications & identifiers

Chemical identifiers
Product name	Olopatadine
Catalogue No.	VQ-007628
CAS Number	113806-05-6
IUPAC name	2-[(11Z)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid
Molecular formula	C₂₁H₂₃NO₃
Molecular weight	337.4 g/mol
Exact mass	337.1678
Grade	Reference Standard
HSN code	38229090
InChIKey	JBIMVDZLSHOPLA-LSCVHKIXSA-N
SMILES	CN(C)CC/C=C\1/C2=CC=CC=C2COC3=C1C=C(C=C3)CC(=O)O
PubChem CID	5281071

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	1 / 4
TPSA	49.8 Å²
Synonyms	(Z)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid, (11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid, 11-[(Z)-3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid, Opatanol, AL-4943A, 11-((Z)-3-(Dimethylamino)propylidene)-6,11-dihydrodibenz(b,e)oxepin-2-acetic acid, 2-((11Z)-11-(3-(dimethylamino)propylidene)-6H-benzo(c)(1)benzoxepin-2-yl)acetic acid, Patanol, Olopatadine (INN), Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-, {(11Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid, 2-[(11Z)-11-[3-(dimethylazaniumyl)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetate

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H400Very toxic to aquatic life

Precautionary statements: P203, P264, P270, P273, P280, P301 + P316, P318, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Olopatadine?

The CAS Registry Number of Olopatadine is 113806-05-6. It is also known as (Z)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid, (11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid, 11-[(Z)-3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid.

What is the molecular formula and molecular weight of Olopatadine?

Olopatadine has the molecular formula C21H23NO3 and a molecular weight of 337.4 g/mol. Its IUPAC name is 2-[(11Z)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid.

What is Olopatadine used for?

Olopatadine is supplied as a characterised reference material related to Olopatadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Olopatadine can I order?

We supply Olopatadine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Olopatadine?

Yes. Every lot of Olopatadine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Olopatadine be shipped internationally?

Yes. Olopatadine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.