Omaveloxolone

Name: Omaveloxolone
Brand: Vaqora Chemicals
SKU: VQ-032259

About Omaveloxolone

Omaveloxolone is an API reference standard carrying the CAS registry number 1474034-05-3. Formula C33H44F2N2O3, molecular weight 554.7 g/mol. Common synonyms include RTA-408 and RTA 408.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this the parent drug substance standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Omaveloxolone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Specifications & identifiers

Chemical identifiers
Product name	Omaveloxolone
Catalogue No.	VQ-032259
CAS Number	1474034-05-3
IUPAC name	N-[(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicen-4a-yl]-2,2-difluoropropanamide
Molecular formula	C₃₃H₄₄F₂N₂O₃
Molecular weight	554.7 g/mol
Exact mass	554.332
Grade	Reference Standard
HSN code	38229090
InChIKey	RJCWBNBKOKFWNY-IDPLTSGASA-N
SMILES	C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)NC(=O)C(C)(F)F
PubChem CID	71811910

Physical properties
Physical form	Solid
LogP (XLogP3)	6.7
H-bond donors / acceptors	1 / 6
TPSA	87 Å²
Synonyms	RTA-408, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide, Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-, RTA 408, Nrf1-activator-1, Omaveloxolone (RTA-408), EX-A541

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Omaveloxolone?

The CAS Registry Number of Omaveloxolone is 1474034-05-3. It is also known as RTA-408, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoropropanamide, Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-.

What is the molecular formula and molecular weight of Omaveloxolone?

Omaveloxolone has the molecular formula C33H44F2N2O3 and a molecular weight of 554.7 g/mol. Its IUPAC name is N-[(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicen-4a-yl]-2,2-difluoropropanamide.

Which grade and pack sizes of Omaveloxolone can I order?

We supply Omaveloxolone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Omaveloxolone?

Yes. Every lot of Omaveloxolone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Omaveloxolone be shipped internationally?

Yes. Omaveloxolone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.