Orlistat open ring epimer

Name: Orlistat open ring epimer
Brand: Vaqora Chemicals
SKU: VQ-027033

About Orlistat open ring epimer

Orlistat open ring epimer (CAS 130793-28-1) is an impurity of Orlistat offered by Vaqora Chemicals. Its molecular formula is C29H55NO6 and its molecular weight is 513.7 g/mol. The IUPAC name is (2S,3R,5S)-5-[(2S)-2-formamido-4-methylpentanoyl]oxy-2-hexyl-3-hydroxyhexadecanoic acid. Alternative names: Orlistat Open Ring (2S,3R,5S)-Isomer and Orlistat open ring epimer (M1).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Orlistat to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Orlistat

View every impurity, metabolite and intermediate we list for Orlistat.

Orlistat impurities

Specifications & identifiers

Chemical identifiers
Product name	Orlistat open ring epimer
Catalogue No.	VQ-027033
CAS Number	130793-28-1
IUPAC name	(2S,3R,5S)-5-[(2S)-2-formamido-4-methylpentanoyl]oxy-2-hexyl-3-hydroxyhexadecanoic acid
Molecular formula	C₂₉H₅₅NO₆
Molecular weight	513.7 g/mol
Exact mass	513.4029
Grade	Reference Standard
HSN code	38229090
InChIKey	FKUNIADJSAJLGB-YIPNQBBMSA-N
SMILES	CCCCCCCCCCC[C@@H](C[C@H]([C@H](CCCCCC)C(=O)O)O)OC(=O)[C@H](CC(C)C)NC=O
PubChem CID	59434860

Physical properties
Physical form	Solid
LogP (XLogP3)	9.2
H-bond donors / acceptors	3 / 6
TPSA	113 Å²
Synonyms	Orlistat Open Ring (2S,3R,5S)-Isomer, L-Leucine, N-formyl-, (1S)-1-((2R,3S)-3-carboxy-2-hydroxynonyl)dodecyl ester, N-Formyl-L-leucine (1S)-1-((2R,3S)-3-carboxy-2-hydroxynonyl)dodecyl ester, (2S,3R,5S)-5-((S)-2-Formylamino-4-methyl-pentanoyloxy)-2-hexyl-3-hydroxy-hexadecanoic acid, N-Formyl-L-leucine (1S)-1-[(2R,3S)-3-carboxy-2-hydroxynonyl]dodecyl ester, L-Leucine, N-formyl-, (1S)-1-[(2R,3S)-3-carboxy-2-hydroxynonyl]dodecyl ester, (2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic acid, Orlistat open ring epimer (M1), [2R-[1(S),2R,3S*]]-N-Formyl-L-Leucine 1-[3-Carboxy-2-hydroxynonyl]dodecyl Ester, (2S,3R,5S)-5-[(2S)-2-formamido-4-methyl-pentanoyl]oxy-2-hexyl-3-hydroxy-hexadecanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Orlistat open ring epimer?

The CAS Registry Number of Orlistat open ring epimer is 130793-28-1. It is also known as Orlistat Open Ring (2S,3R,5S)-Isomer, L-Leucine, N-formyl-, (1S)-1-((2R,3S)-3-carboxy-2-hydroxynonyl)dodecyl ester, N-Formyl-L-leucine (1S)-1-((2R,3S)-3-carboxy-2-hydroxynonyl)dodecyl ester.

What is the molecular formula and molecular weight of Orlistat open ring epimer?

Orlistat open ring epimer has the molecular formula C29H55NO6 and a molecular weight of 513.7 g/mol. Its IUPAC name is (2S,3R,5S)-5-[(2S)-2-formamido-4-methylpentanoyl]oxy-2-hexyl-3-hydroxyhexadecanoic acid.

What is Orlistat open ring epimer used for?

Orlistat open ring epimer is supplied as a characterised reference material related to Orlistat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Orlistat open ring epimer can I order?

We supply Orlistat open ring epimer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Orlistat open ring epimer?

Yes. Every lot of Orlistat open ring epimer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Orlistat open ring epimer be shipped internationally?

Yes. We export Orlistat open ring epimer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.