Palbociclib Chlorobromo Impurity

Name: Palbociclib Chlorobromo Impurity
Brand: Vaqora Chemicals
SKU: VQ-005458

About Palbociclib Chlorobromo Impurity

Palbociclib Chlorobromo Impurity is an impurity of Palbociclib carrying the CAS registry number 1016636-76-2. Its molecular formula is C13H13BrClN3O and its molecular weight is 342.62 g/mol. The IUPAC name is 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one. Common synonyms include Palbociclib Impurity 58 and Palbociclib Impurity 25.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Palbociclib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Palbociclib Chlorobromo Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Palbociclib Chlorobromo Impurity
Catalogue No.	VQ-005458
CAS Number	1016636-76-2
IUPAC name	6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one
Molecular formula	C₁₃H₁₃BrClN₃O
Molecular weight	342.62 g/mol
Exact mass	340.993
Grade	Reference Standard
HSN code	38229090
InChIKey	HJQCAEDIUJXGCQ-UHFFFAOYSA-N
SMILES	CC1=C(C(=O)N(C2=NC(=NC=C12)Cl)C3CCCC3)Br
PubChem CID	44248249

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	0 / 3
TPSA	46.1 Å²
Synonyms	6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one, 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one, 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one, Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-bromo-2-chloro-8-cyclopentyl-5-methyl-, 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one, 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido(2,3-d)pyrimidin-7(8H)-one, Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-bromo-2-chloro-8-cyclopentyl-5-methyl-, 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one, Palbociclib Impurity 58, 6-Bromo-8-cyclopentyl-2-chloro-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one, Palbociclib Impurity 25, 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one, AldrichCPR

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P233, P260, P261, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 1016636-76-2

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one, 98%

CAS: 1016636-76-2
Formula: C₁₃H₁₃BrClN₃O
MW: 342.62 g/mol

VQ-012084

Frequently asked questions

What is the CAS number of Palbociclib Chlorobromo Impurity?

The CAS Registry Number of Palbociclib Chlorobromo Impurity is 1016636-76-2. It is also known as 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one, 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one, 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one.

What is the molecular formula and molecular weight of Palbociclib Chlorobromo Impurity?

Palbociclib Chlorobromo Impurity has the molecular formula C13H13BrClN3O and a molecular weight of 342.62 g/mol. Its IUPAC name is 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one.

What is Palbociclib Chlorobromo Impurity used for?

Palbociclib Chlorobromo Impurity is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palbociclib Chlorobromo Impurity can I order?

We supply Palbociclib Chlorobromo Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palbociclib Chlorobromo Impurity?

Yes. Every lot of Palbociclib Chlorobromo Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palbociclib Chlorobromo Impurity be shipped internationally?

Yes. Palbociclib Chlorobromo Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.