Palbociclib Intermediate 4

Name: Palbociclib Intermediate 4
Brand: Vaqora Chemicals
SKU: VQ-013696

About Palbociclib Intermediate 4

Listed under CAS 571188-59-5, Palbociclib Intermediate 4 is a process intermediate or related compound of Palbociclib available from Vaqora Chemicals. With the molecular formula C14H22N4O2, it has a molar mass of 278.35 g/mol. The IUPAC name is tert-butyl 4-(6-amino-3-pyridinyl)piperazine-1-carboxylate. It is also known as 1-Boc-4-(6-aminopyridin-3-yl)piperazine or 4-(6-Amino-3-pyridyl)-1-Boc-piperazine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Palbociclib, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Palbociclib Intermediate 4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Palbociclib

View every impurity, metabolite and intermediate we list for Palbociclib.

Palbociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Palbociclib Intermediate 4
Catalogue No.	VQ-013696
CAS Number	571188-59-5
IUPAC name	tert-butyl 4-(6-amino-3-pyridinyl)piperazine-1-carboxylate
Molecular formula	C₁₄H₂₂N₄O₂
Molecular weight	278.35 g/mol
Exact mass	278.1743
Grade	Reference Standard
HSN code	2933
InChIKey	RMULRXHUNOVPEI-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1CCN(CC1)C2=CN=C(C=C2)N
PubChem CID	11737525

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	1 / 5
TPSA	71.7 Å²
Synonyms	1-Boc-4-(6-aminopyridin-3-yl)piperazine, 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester, tert-Butyl 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylate, tert-Butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate, 1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester, 4-(6-Amino-3-pyridyl)-1-Boc-piperazine, 4-(6-Amino-3-pyridyl)piperazine-1-carboxylic Acid tert-Butyl Ester, 4-(6-amino-pyridin-3-yl)-piperazine-1-carboxyic acid tert-butyl ester, 1-Boc-4-(6-amino-3-pyridyl)piperazine, Palbociclib Intermediates, tert-Butyl4-(6-aminopyridin-3-yl)piperazine-1-carboxylate, 4-(6-Aminopyridin-3-yl)piperazin

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 571188-59-5

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate, 98%

CAS: 571188-59-5
Formula: C₁₄H₂₂N₄O₂
MW: 278.35 g/mol

VQ-011896

Frequently asked questions

What is the CAS number of Palbociclib Intermediate 4?

The CAS Registry Number of Palbociclib Intermediate 4 is 571188-59-5. It is also known as 1-Boc-4-(6-aminopyridin-3-yl)piperazine, 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester, tert-Butyl 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylate.

What is the molecular formula and molecular weight of Palbociclib Intermediate 4?

Palbociclib Intermediate 4 has the molecular formula C14H22N4O2 and a molecular weight of 278.35 g/mol. Its IUPAC name is tert-butyl 4-(6-amino-3-pyridinyl)piperazine-1-carboxylate.

What is Palbociclib Intermediate 4 used for?

Palbociclib Intermediate 4 is supplied as a characterised reference material related to Palbociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palbociclib Intermediate 4 can I order?

We supply Palbociclib Intermediate 4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palbociclib Intermediate 4?

Yes. Every lot of Palbociclib Intermediate 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palbociclib Intermediate 4 be shipped internationally?

Yes. Palbociclib Intermediate 4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.