Palonosetron (RS-Isomer)

Name: Palonosetron (RS-Isomer)
Brand: Vaqora Chemicals
SKU: VQ-005481

About Palonosetron (RS-Isomer)

Vaqora Chemicals supplies Palonosetron (RS-Isomer), an impurity of Palonosetron registered under CAS number 149654-00-2. Formula C19H24N2O, molecular weight 296.4 g/mol. The IUPAC name is (3aS)-2-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one. Common synonyms include Palonosetron, (3R)- and RS-25233-197 free base.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Palonosetron, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Palonosetron

View every impurity, metabolite and intermediate we list for Palonosetron.

Palonosetron impurities

Specifications & identifiers

Chemical identifiers
Product name	Palonosetron (RS-Isomer)
Catalogue No.	VQ-005481
CAS Number	149654-00-2
Other CAS	135729-76-9
IUPAC name	(3aS)-2-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
Molecular formula	C₁₉H₂₄N₂O
Molecular weight	296.4 g/mol
Exact mass	296.1889
Grade	Reference Standard
HSN code	38229090
InChIKey	CPZBLNMUGSZIPR-WBVHZDCISA-N
SMILES	C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@H]4CN5CCC4CC5
PubChem CID	15656883

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 2
TPSA	23.6 Å²
Synonyms	(S)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one, (S)-2-[(3R)-Quinuclidin-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one, Palonosetron, (3R)-, RS-25233-197 free base, 2-(1-Azabicyclo-[2.2.2]oct-3R-yl)-2,3,3aS,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Palonosetron (RS-Isomer)?

The CAS Registry Number of Palonosetron (RS-Isomer) is 149654-00-2. It is also known as (S)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one, (S)-2-[(3R)-Quinuclidin-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one, Palonosetron, (3R)-.

What is the molecular formula and molecular weight of Palonosetron (RS-Isomer)?

Palonosetron (RS-Isomer) has the molecular formula C19H24N2O and a molecular weight of 296.4 g/mol. Its IUPAC name is (3aS)-2-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one.

What is Palonosetron (RS-Isomer) used for?

Palonosetron (RS-Isomer) is supplied as a characterised reference material related to Palonosetron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Palonosetron (RS-Isomer) can I order?

We supply Palonosetron (RS-Isomer) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Palonosetron (RS-Isomer)?

Yes. Every lot of Palonosetron (RS-Isomer) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Palonosetron (RS-Isomer) be shipped internationally?

Yes. We export Palonosetron (RS-Isomer) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.