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VAQORACHEMICALS
API ImpuritiesReference Standard In stock

Pazopanib Impurity A

Synonyms: N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine · N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine · Pazopanib Impurity 12 · Pazopanib related

CAS No.444731-75-3
FormulaC14H14ClN5
Mol. weight287.75
Catalogue No.VQ-005494
PurityReference Standard
HSN38229090

Pazopanib Impurity A (CAS 444731-75-3) – Pazopanib impurity standard. C14H14ClN5, MW 287.75. Order from Vaqora Chemicals with COA and global delivery.

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1 g
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About Pazopanib Impurity A

Listed under CAS 444731-75-3, Pazopanib Impurity A is an impurity of Pazopanib available from Vaqora Chemicals. Its molecular formula is C14H14ClN5 and its molecular weight is 287.75 g/mol. The IUPAC name is N-(2-chloropyrimidin-4-yl)-N,2,3-trimethylindazol-6-amine. Alternative names: Pazopanib Impurity 12 and Pazopanib related.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Pazopanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Pazopanib Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Pazopanib

View every impurity, metabolite and intermediate we list for Pazopanib.

Pazopanib impurities

Specifications & identifiers

Chemical identifiers
Product namePazopanib Impurity A
Catalogue No.VQ-005494
CAS Number444731-75-3
IUPAC nameN-(2-chloropyrimidin-4-yl)-N,2,3-trimethylindazol-6-amine
Molecular formulaC14H14ClN5
Molecular weight287.75 g/mol
Exact mass287.0938
GradeReference Standard
HSN code38229090
InChIKeyDVGMRZQSSNNTFY-UHFFFAOYSA-N
SMILESCC1=C2C=CC(=CC2=NN1C)N(C)C3=NC(=NC=C3)Cl
PubChem CID11608962
Physical properties
Physical formSolid
LogP (XLogP3)3.2
H-bond donors / acceptors0 / 4
TPSA46.8 Ų
SynonymsN-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine, N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine, Pazopanib Impurity 12, Pazopanib related, 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl-, (2-Chlo, N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-indazol-6-amine, CS-B0769, 6-[N-(2-chloro-4-pyrimidinyl)methylamino]-2,3-dimethyl-2H-indazole, N-(2-chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2h-indazole-6-amine

Safety & hazard information (GHS)

GHS06 Toxic
Toxic
GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard

Signal word: Danger

Hazard statements

  • H301Toxic if swallowed
  • H302Harmful if swallowed
  • H319Causes serious eye irritation
  • H341Suspected of causing genetic defects
  • H361Suspected of damaging fertility or the unborn child
  • H362May cause harm to breast-fed children
  • H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P264 + P265, P270, P273, P280, P301 + P316, P301 + P317, P305 + P351 + P338, P318, P321, P330, P337 + P317, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Pazopanib Impurity A?

The CAS Registry Number of Pazopanib Impurity A is 444731-75-3. It is also known as N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine, N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine, Pazopanib Impurity 12.

What is the molecular formula and molecular weight of Pazopanib Impurity A?

Pazopanib Impurity A has the molecular formula C14H14ClN5 and a molecular weight of 287.75 g/mol. Its IUPAC name is N-(2-chloropyrimidin-4-yl)-N,2,3-trimethylindazol-6-amine.

What is Pazopanib Impurity A used for?

Pazopanib Impurity A is supplied as a characterised reference material related to Pazopanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pazopanib Impurity A can I order?

We supply Pazopanib Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pazopanib Impurity A?

Yes. Every lot of Pazopanib Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pazopanib Impurity A be shipped internationally?

Yes. Pazopanib Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about Pazopanib Impurity A

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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Related products

Reference Standard
Pazopanib chemical structure
Pazopanib
CAS
444731-52-6
Formula
C21H23N7O2S
MW
437.5 g/mol
VQ-007644

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