Pazopanib Impurity A
Synonyms: N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine · N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine · Pazopanib Impurity 12 · Pazopanib related
Pazopanib Impurity A (CAS 444731-75-3) – Pazopanib impurity standard. C14H14ClN5, MW 287.75. Order from Vaqora Chemicals with COA and global delivery.
About Pazopanib Impurity A
Listed under CAS 444731-75-3, Pazopanib Impurity A is an impurity of Pazopanib available from Vaqora Chemicals. Its molecular formula is C14H14ClN5 and its molecular weight is 287.75 g/mol. The IUPAC name is N-(2-chloropyrimidin-4-yl)-N,2,3-trimethylindazol-6-amine. Alternative names: Pazopanib Impurity 12 and Pazopanib related.
The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.
Pharmaceutical QC and development laboratories use this impurity standard of Pazopanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies Pazopanib Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Pazopanib.
Pazopanib impuritiesSpecifications & identifiers
| Product name | Pazopanib Impurity A |
|---|---|
| Catalogue No. | VQ-005494 |
| CAS Number | 444731-75-3 |
| IUPAC name | N-(2-chloropyrimidin-4-yl)-N,2,3-trimethylindazol-6-amine |
| Molecular formula | C14H14ClN5 |
| Molecular weight | 287.75 g/mol |
| Exact mass | 287.0938 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | DVGMRZQSSNNTFY-UHFFFAOYSA-N |
| SMILES | CC1=C2C=CC(=CC2=NN1C)N(C)C3=NC(=NC=C3)Cl |
| PubChem CID | 11608962 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3.2 |
| H-bond donors / acceptors | 0 / 4 |
| TPSA | 46.8 Ų |
| Synonyms | N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine, N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine, Pazopanib Impurity 12, Pazopanib related, 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl-, (2-Chlo, N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-indazol-6-amine, CS-B0769, 6-[N-(2-chloro-4-pyrimidinyl)methylamino]-2,3-dimethyl-2H-indazole, N-(2-chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2h-indazole-6-amine |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H301Toxic if swallowedH302Harmful if swallowedH319Causes serious eye irritationH341Suspected of causing genetic defectsH361Suspected of damaging fertility or the unborn childH362May cause harm to breast-fed childrenH412Harmful to aquatic life with long lasting effects
Precautionary statements: P203, P260, P263, P264, P264 + P265, P270, P273, P280, P301 + P316, P301 + P317, P305 + P351 + P338, P318, P321, P330, P337 + P317, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Pazopanib Impurity A?
The CAS Registry Number of Pazopanib Impurity A is 444731-75-3. It is also known as N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine, N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine, Pazopanib Impurity 12.
What is the molecular formula and molecular weight of Pazopanib Impurity A?
Pazopanib Impurity A has the molecular formula C14H14ClN5 and a molecular weight of 287.75 g/mol. Its IUPAC name is N-(2-chloropyrimidin-4-yl)-N,2,3-trimethylindazol-6-amine.
What is Pazopanib Impurity A used for?
Pazopanib Impurity A is supplied as a characterised reference material related to Pazopanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Pazopanib Impurity A can I order?
We supply Pazopanib Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Pazopanib Impurity A?
Yes. Every lot of Pazopanib Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Pazopanib Impurity A be shipped internationally?
Yes. Pazopanib Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Pazopanib Impurity A
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