Pemetrexed Dimethyl Ester

Name: Pemetrexed Dimethyl Ester
Brand: Vaqora Chemicals
SKU: VQ-027416

About Pemetrexed Dimethyl Ester

Vaqora Chemicals supplies Pemetrexed Dimethyl Ester, an impurity of Pemetrexed registered under CAS number 155405-81-5. Its molecular formula is C22H25N5O6 and its molecular weight is 455.5 g/mol. It is also known as Pemetrexed Methyl Ester or Pemetrexed Dimethyl Ester, S-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Pemetrexed to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Pemetrexed Dimethyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pemetrexed

View every impurity, metabolite and intermediate we list for Pemetrexed.

Pemetrexed impurities

Specifications & identifiers

Chemical identifiers
Product name	Pemetrexed Dimethyl Ester
Catalogue No.	VQ-027416
CAS Number	155405-81-5
IUPAC name	dimethyl (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
Molecular formula	C₂₂H₂₅N₅O₆
Molecular weight	455.5 g/mol
Exact mass	455.1805
Grade	Reference Standard
HSN code	38229090
InChIKey	WWYZIXUUERDREV-HNNXBMFYSA-N
SMILES	COC(=O)CC[C@@H](C(=O)OC)NC(=O)C1=CC=C(C=C1)CCC2=CNC3=C2C(=O)NC(=N3)N
PubChem CID	136120839

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	4 / 7
TPSA	165 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pemetrexed Dimethyl Ester?

The CAS Registry Number of Pemetrexed Dimethyl Ester is 155405-81-5. It is also known as Pemetrexed Methyl Ester, Pemetrexed Dimethyl Ester, S-, (E)-4-(4-((2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)imino)butyl)benzoic acid.

What is the molecular formula and molecular weight of Pemetrexed Dimethyl Ester?

Pemetrexed Dimethyl Ester has the molecular formula C22H25N5O6 and a molecular weight of 455.5 g/mol. Its IUPAC name is dimethyl (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate.

What is Pemetrexed Dimethyl Ester used for?

Pemetrexed Dimethyl Ester is supplied as a characterised reference material related to Pemetrexed. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pemetrexed Dimethyl Ester can I order?

We supply Pemetrexed Dimethyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pemetrexed Dimethyl Ester?

Yes. Every lot of Pemetrexed Dimethyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pemetrexed Dimethyl Ester be shipped internationally?

Yes. We export Pemetrexed Dimethyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.